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European Journal of Applied Physiology

, Volume 117, Issue 5, pp 1005–1015 | Cite as

The effect of eccentric exercise with blood flow restriction on neuromuscular activation, microvascular oxygenation, and the repeated bout effect

  • Jakob D. LauverEmail author
  • Trent E. Cayot
  • Timothy Rotarius
  • Barry W. Scheuermann
Original Article

Abstract

Purpose

To examine the effect of low-intensity eccentric contractions with and without blood flow restriction (BFR) on microvascular oxygenation, neuromuscular activation, and the repeated bout effect (RBE).

Methods

Participants were randomly assigned to either low-intensity (LI), low-intensity with BFR (LI-BFR), or a control (CON) group. Participants in LI and LI-BFR performed a preconditioning bout of low-intensity eccentric exercise prior to about of maximal eccentric exercise. Participants reported 24, 48, 72, and 96 h later to assess muscle damage and function. Surface electromyography (sEMG) and near-infrared spectroscopy (NIRS) were used to measure neuromuscular activation and microvascular deoxygenation (deoxy-[Hb + Mb]) and [total hemoglobin] ([THC]) during the preconditioning bout, respectively.

Results

During set-2, LI-BFR resulted in greater activation of the VM-RMS (47.7 ± 11.5% MVIC) compared to LI (67.0 ± 20.0% MVIC), as well as during set-3 (p < 0.05). LI-BFR resulted in a greater change in deoxy-[Hb + Mb] compared to LI during set-2 (LI-BFR 13.1 ± 5.2 µM, LI 6.7 ± 7.9 µM), set-3 (LI-BFR 14.6 ± 6 µM, LI 6.9 ± 7.4 µM), and set-4 (p < 0.05). [THC] was higher during LI-BFR compared to LI (p < 0.05). All groups showed a decrease in MVIC torque immediately after maximal exercise (LI 74.2 ± 14.1%, LI-BFR 75 ± 5.1%, CON 53 ± 18.6%). At 24, 48, 72, and 96 h post maximal eccentric exercise, LI and LI-BFR force deficit was not different from baseline.

Conclusion

This study suggests that the neuromuscular and deoxygenation (i.e., metabolic stress) responses were considerably different between LI and LI-BFR groups; however, these differences did not lead to improvements in the RBE inferred by performing LI and LI-BFR.

Keywords

Blood flow restriction Repeated bout effect Near-infrared spectroscopy 

Abbreviations

ANOVA

Analysis of variance

BFR

Blood flow restriction

CON

Control

deoxy-[Hb + Mb]

Deoxyhemoglobin

EIMG

Exercise-induced muscle damage

LI

Low intensity

LI-BFR

Low intensity with blood flow restriction

MVIC

Maximal voluntary isometric contraction

NIRS

Near-infrared spectroscopy

RBE

Repeated bout effect

RM

Repetition maximum

RMS

Root mean square

SD

Standard deviation

sEMG

Surface electromyography

[THC]

Total hemoglobin concentration

Notes

Acknowledgements

The authors would like to thank the subjects for volunteering to participate in this study.

Compliance with ethical standards

Conflict of interest

The authors declare no conflict of interest.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Jakob D. Lauver
    • 1
    • 2
    Email author
  • Trent E. Cayot
    • 1
    • 3
  • Timothy Rotarius
    • 1
  • Barry W. Scheuermann
    • 1
  1. 1.Department of Exercise and Rehabilitative SciencesUniversity of ToledoToledoUSA
  2. 2.Department of Exercise Science and Athletic TrainingAdrian CollegeAdrianUSA
  3. 3.Division of Mathematics, Computer and Natural SciencesOhio Dominican UniversityColumbusUSA

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