European Journal of Applied Physiology

, Volume 111, Issue 2, pp 313–318 | Cite as

The influence of aerobic exercise training on the double product break point in low-to-moderate risk adults

  • Trent A. Hargens
  • Diane C. Griffin
  • Leonard A. Kaminsky
  • Mitchell H. Whaley
Original Article


The double product is the product of the heart rate and systolic blood pressure. The double product break point (DPBP) is a physiologic threshold that occurs at similar exercise intensities to that of the ventilatory threshold (VT). The influence of aerobic exercise training on the DPBP has not yet been examined. The purpose of this study was to examine whether aerobic exercise training (ET) increases the exercise intensity at which the DPBP occurs, and whether it increases in a similar fashion to the VT. Seven males and 11 females, all sedentary (mean ± SD: age = 29.9 ± 10.5 years) underwent supervised cardiopulmonary exercise testing using a cycle ergometer ramp protocol at baseline and after 8 weeks of vigorous ET on a cycle ergometer. The VT was determined by gas analysis and the V-slope method. Experienced observers using standardized instructions visually determined the DPBP. Following ET, VO2peak, maximal workload, and body composition variables all showed significant positive changes. The VO2 at which the DPBP and VT occurred increased significantly from baseline to follow-up (P < 0.001). At baseline and at follow-up, the DPBP and VT did not differ. The DPBP and VT were significantly correlated to each other at both time points. Results suggest that the DPBP responds to ET in a similar fashion to that of the VT, and may be an easier and more useful marker of the VT for exercise training purposes.


Exercise training Double product break point Ventilatory threshold Cardiopulmonary exercise testing 


  1. American College of Sports Medicine, Thompson WR, Gordon NF, Pescatello LS (2010) ACSM’s guidelines for exercise testing and prescription. Lippincott Williams and Wilkins, PhiladelphiaGoogle Scholar
  2. Arya A, Maleki M, Noohi F, Kassaian E, Roshanali F (2005) Myocardial oxygen consumption index in patients with coronary artery disease. Asian Cardiovasc Thorac Ann 13:34–37PubMedGoogle Scholar
  3. Beaver WL, Wasserman K, Whipp BJ (1986) A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 60:2020–2027PubMedGoogle Scholar
  4. Brubaker PH, Kiyonaga A, Matrazzo BA, Pollock WE, Shindo M, Miller HS Jr, Tanaka H (1997) Identification of the anaerobic threshold using double product in patients with coronary artery disease. Am J Cardiol 79:360–362CrossRefPubMedGoogle Scholar
  5. Brubaker PH, Kaminsky LA, Whaley MH (2002) Coronary artery disease : essentials of prevention and rehabilitation programs. Human Kinetics, Champaign, ILGoogle Scholar
  6. Cameron JD, Stevenson I, Reed E, McGrath BP, Dart AM, Kingwell BA (2004) Accuracy of automated auscultatory blood pressure measurement during supine exercise and treadmill stress electrocardiogram-testing. Blood Press Monit 9:269–275CrossRefPubMedGoogle Scholar
  7. Davis JA, Frank MH, Whipp BJ, Wasserman K (1979) Anaerobic threshold alterations caused by endurance training in middle-aged men. J Appl Physiol 46:1039–1046PubMedGoogle Scholar
  8. Durstine JL, American College of Sports Medicine (2009) ACSM’s exercise management for persons with chronic diseases and disabilities. Human Kinetics, Champaign, ILGoogle Scholar
  9. Furtado EC, Ramos Pdos S, Araujo CG (2009) Blood pressure measurement during aerobic exercise: subsidies for cardiac rehabilitation. Arq Bras Cardiol 93:45–52CrossRefPubMedGoogle Scholar
  10. Gobel FL, Norstrom LA, Nelson RR, Jorgensen CR, Wang Y (1978) The rate-pressure product as an index of myocardial oxygen consumption during exercise in patients with angina pectoris. Circulation 57:549–556PubMedGoogle Scholar
  11. Jensen BE, Fletcher BJ, Rupp JC, Fletcher GF, Lee JY, Oberman A (1996) Training level comparison study effect of high and low intensity exercise on ventilatory threshold in men with coronary artery disease. J Cardiopulm Rehabil 16:227–232CrossRefPubMedGoogle Scholar
  12. Jones AM, Carter H (2000) The effect of endurance training on parameters of aerobic fitness. Sports Med 29:373–386CrossRefPubMedGoogle Scholar
  13. Jorgensen CR, Wang K, Wang Y, Gobel FL, Nelson RR, Taylor H (1973) Effect of propranolol on myocardial oxygen consumption and its hemodynamic correlates during upright exercise. Circulation 48:1173–1182PubMedGoogle Scholar
  14. Kim KT, Choi SW, Takahashi K, Kurokawa T, Yamasaki M (2003) Change in double product during stepwise incremental exercise. J Physiol Anthropol Appl Human Sci 22:143–147CrossRefPubMedGoogle Scholar
  15. Kitamura K, Jorgensen CR, Gobel FL, Taylor HL, Wang Y (1972) Hemodynamic correlates of myocardial oxygen consumption during upright exercise. J Appl Physiol 32:516–522PubMedGoogle Scholar
  16. Mazzeo RS, Marshall P (1989) Influence of plasma catecholamines on the lactate threshold during graded exercise. J Appl Physiol 67:1319–1322PubMedGoogle Scholar
  17. McConnell TR, Clark BAI, Conlin NC, Haas JH (1993) Gas exchange anaerobic threshold: Implications for prescribing exercise in cardiac rehabilitation. J Cardiopulm Rehabil Prev 13:31–36CrossRefGoogle Scholar
  18. Omiya K, Itoh H, Harada N, Maeda T, Tajima A, Oikawa K, Koike A, Aizawa T, Fu LT, Osada N (2004) Relationship between double product break point, lactate threshold, and ventilatory threshold in cardiac patients. Eur J Appl Physiol 91:224–229CrossRefPubMedGoogle Scholar
  19. Poole DC, Gaesser GA (1985) Response of ventilatory and lactate thresholds to continuous and interval training. J Appl Physiol 58:1115–1121PubMedGoogle Scholar
  20. Riley M, Maehara K, Porszasz J, Engelen MP, Bartstow TJ, Tanaka H, Wasserman K (1997) Association between the anaerobic threshold and the break-point in the double product/work rate relationship. Eur J Appl Physiol Occup Physiol 75:14–21CrossRefPubMedGoogle Scholar
  21. Svedahl K, MacIntosh BR (2003) Anaerobic threshold: the concept and methods of measurement. Can J Appl Physiol 28:299–323PubMedGoogle Scholar
  22. Tanabe K, Osada N, Noda K, Yamamoto M, Omiya K, Itoh H, Kamegai M, Murayama M, Sugai J (1994) Changes in hemodynamics and catecholamines during single-level exercise at the anaerobic threshold and 120% of the anaerobic threshold in normal subjects. J Cardiol 24:61–69PubMedGoogle Scholar
  23. Tanaka K, Matsuura Y (1984) Marathon performance, anaerobic threshold, and onset of blood lactate accumulation. J Appl Physiol 57:640–643PubMedGoogle Scholar
  24. Tanaka H, Shindo M (1992) The benefits of the low intensity training. Ann Physiol Anthropol 11:365–368PubMedGoogle Scholar
  25. Tanaka K, Matsuura Y, Matsuzaka A, Hirakoba K, Kumagai S, Sun SO, Asano K (1984) A longitudinal assessment of anaerobic threshold and distance-running performance. Med Sci Sports Exerc 16:278–282PubMedGoogle Scholar
  26. Tanaka H, Kiyonaga A, Terao Y, Ide K, Yamauchi M, Tanaka M, Shindo M (1997) Double product response is accelerated above the blood lactate threshold. Med Sci Sports Exerc 29:503–508PubMedGoogle Scholar
  27. Wasserman K, Whipp BJ, Koyl SN, Beaver WL (1973) Anaerobic threshold and respiratory gas exchange during exercise. J Appl Physiol 35:236–243PubMedGoogle Scholar
  28. Winder WW, Hagberg JM, Hickson RC, Ehsani AA, McLane JA (1978) Time course of sympathoadrenal adaptation to endurance exercise training in man. J Appl Physiol 45:370–374PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Trent A. Hargens
    • 1
  • Diane C. Griffin
    • 1
  • Leonard A. Kaminsky
    • 1
  • Mitchell H. Whaley
    • 2
  1. 1.Clinical Exercise Physiology Program, Human Performance LabBall State UniversityMuncieUSA
  2. 2.College of Applied Sciences and TechnologyBall State UniversityMuncieINUSA

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