20-Hz whole body vibration training fails to counteract the decrease in leg muscle volume caused by 14 days of 6° head down tilt bed rest

  • Jochen Zange
  • Joachim Mester
  • Martina Heer
  • Götz Kluge
  • Anna-Maria Liphardt
Original Article


A 6° head down tilt bed rest (HDT) was used to simulate the effects of muscle unloading in space. We tested whether vibration training (VT) reduces the decrease in leg muscle volume induced by 14 days HDT. In two study phases eight healthy male subjects received both (1) HDT and VT or (2) HDT and a control intervention. Twice daily five intervals of 1 min VT were performed (20 Hz, 2–4 mm) in upright standing position followed by 1 min breaks in seated position. The control intervention included identical procedures except the vibration plate was off. Before and the day after HDT volumes of upper and lower leg muscles were measured using magnetic resonance imaging. HDT combined with control intervention caused a significant (P < 0.05) decrease in the volumes of muscles by −4 to −6.5%. VT failed to counteract the decrease in leg muscle volume induced by HDT.


Magnetic resonance imaging Muscle atrophy Countermeasure Space flight Immobilisation 


  1. Alkner BA, Tesch PA (2004) Knee extensor and plantar flexor muscle size and function following 90 days of bed rest with or without resistance exercise. Eur J Appl Physiol 93(3):294–305PubMedCrossRefGoogle Scholar
  2. Antonutto G, Capelli C, Girardis M, Zamparo P, Di Prampero PE (1999) Effects of microgravity on maximal power of lower limbs during very short efforts in humans. J Appl Physiol 86:85–92PubMedGoogle Scholar
  3. Blottner D, Salanova M, Puttmann B, Schiffl G, Felsenberg D, Buehring B, Rittweger J (2006) Human skeletal muscle structure and function preserved by vibration muscle exercise following 55 days of bed rest. Eur J Appl Physiol 91(3):261–271CrossRefGoogle Scholar
  4. Bosco C, Iacovelli M, Tsarpela O, Cardinale M, Bonifazi M, Tihanyi J, Viru M, De Lorenzo A, Viru A (2000) Hormonal responses to whole-body vibration in men. Eur J Appl Physiol 81:449–454. doi:10.1007/s004210050067 PubMedCrossRefGoogle Scholar
  5. Burke D, Hagbarth KE, Lofstedt L, Wallin BG (1976) The responses of human muscle spindle endings to vibration during isometric contraction. J Physiol 261:695–711PubMedGoogle Scholar
  6. Cardinale M, Wakeling J (2005) Whole body vibration exercise: are vibrations good for you? Br J Sports Med 39:585–589. doi:10.1136/bjsm.2005.016857 PubMedCrossRefGoogle Scholar
  7. Desmedt JE, Godaux E (1978) Mechanism of the vibration paradox: excitatory and inhibitory effects of tendon vibration on single soleus muscle motor units in man. J Physiol 285:197–207PubMedGoogle Scholar
  8. Di Prampero PE, Narici MV (2003) Muscles in microgravity: from fibres to human motion. J Biomech 36:403–412. doi:10.1016/S0021-9290(02)00418-9 PubMedCrossRefGoogle Scholar
  9. Hagbarth KE, Hellsing G, Lofstedt L (1976) TVR and vibration-induced timing of motor impulses in the human jaw elevator muscles. J Neurol Neurosurg Psychiatry 39:719–728PubMedCrossRefGoogle Scholar
  10. Heer M, Baisch F, Kropp J, Gerzer R, Drummer C (2000) High dietary sodium chloride consumption may not induce body fluid retention in humans. Am J Physiol Renal Physiol 278:F585–F595PubMedGoogle Scholar
  11. Issurin VB (2005) Vibrations and their applications in sport: a review. J Sports Med Phys Fitness 45:324–336PubMedGoogle Scholar
  12. Jordan MJ, Norris SR, Smith DJ, Herzog W (2005) Vibration training: an overview of the area, training consequences, and future considerations. J Strength Cond Res 19:459–466. doi:10.1519/13293.1 PubMedCrossRefGoogle Scholar
  13. LeBlanc A, Lin C, Shackelford L, Sinitsyn V, Evans H, Belichenko O, Schenkman B, Kozlovskaya I, Oganov V, Bakulin A, Hedrick T, Feeback D (2000) Muscle volume, MRI relaxation times (T2), and body composition after spaceflight. J Appl Physiol 89:2158–2164PubMedGoogle Scholar
  14. LeBlanc AD, Spector ER, Evans HJ, Sibonga JD (2007) Skeletal responses to space flight and the bed rest analog: a review. J Musculoskelet Neuronal Interact 7:33–47PubMedGoogle Scholar
  15. Liphardt AM, Bäcker N, Mündermann A, Koo S, Andriacci T, Zange J, Kleinöder H, Mester J (2008) The potential of whole body vibration training to integratively counteract the effects of 14-days of immobilization. In: Cabri J, Alves F, Araújo D, Barreiros J, Diniz J, Veloso A (eds) Book of abstract of the 13th annual meeting of the European college of sport science in Estoril, Portugal from 9 to 12 July 2008, pp 69Google Scholar
  16. Luo J, McNamara B, Moran K (2005) The use of vibration training to enhance muscle strength and power. Sports Med 35:23–41. doi:10.2165/00007256-200535010-00003 PubMedCrossRefGoogle Scholar
  17. Mester J, Kleinöder H, Yue Z (2006) Vibration training: benefits and risks. J Biomech 39:1056–1065. doi:10.1016/j.jbiomech.2005.02.015 PubMedCrossRefGoogle Scholar
  18. Mulder ER, Stegeman DF, Gerrits KH, Paalman MI, Rittweger J, Felsenberg D, De Haan A (2006) Strength, size and activation of knee extensors followed during 8 weeks of horizontal bed rest and the influence of a countermeasure. Eur J Appl Physiol 97:706–715. doi:10.1007/s00421-006-0241-6 PubMedCrossRefGoogle Scholar
  19. Nordlund MM, Thorstensson A (2007) Strength training effects of whole-body vibration? Scand J Med Sci Sports 17:12–27PubMedGoogle Scholar
  20. Pierre MC, Genc KO, Litow M, Humphreys B, Rice AJ, Maender CC, Cavanagh PR (2006) Comparison of knee motion on earth and in space: an observational study. J Neuroengineering Rehabil 3:8. doi:10.1186/1743-0003-3-8 CrossRefGoogle Scholar
  21. Pike RL, Brown ML (1984) Nutrition. An integrated approach, Wiley, New YorkGoogle Scholar
  22. Rennie MJ, Wackerhage H, Spangenburg EE, Booth FW (2004) Control of the size of the human muscle mass. Annu Rev Physiol 66:1–30. doi:10.1146/annurev.physiol.66.052102.134444 CrossRefGoogle Scholar
  23. Rittweger J, Beller G, Felsenberg D (2000) Acute physiological effects of exhaustive whole-body vibration exercise in man. Clin Physiol 20:134–142. doi:10.1046/j.1365-2281.2000.00238.x PubMedCrossRefGoogle Scholar
  24. Rittweger J, Ehrig J, Just K, Mutschelknauss M, Kirsch KA, Felsenberg D (2002) Oxygen uptake in whole-body vibration exercise: influence of vibration frequency, amplitude, and external load. Int J Sports Med 23:428–432. doi:10.1055/s-2002-33739 PubMedCrossRefGoogle Scholar
  25. Rittweger J, Frost HM, Schiessl H, Ohshima H, Alkner B, Tesch P, Felsenberg D (2005) Muscle atrophy and bone loss after 90 days’ bed rest and the effects of flywheel resistive exercise and pamidronate: results from the LTBR study. Bone 36:1019–1029. doi:10.1016/j.bone.2004.11.014 PubMedCrossRefGoogle Scholar
  26. Wakeling JM, Liphardt AM (2006) Task-specific recruitment of motor units for vibration damping. J Biomech 39:1342–1346. doi:10.1016/j.jbiomech.2005.03.009 PubMedCrossRefGoogle Scholar
  27. Zange J, Müller K, Schuber M, Wackerhage H, Hoffmann U, Günter RW, Adam G, Neuerburg JM, Sinitsyn VE, Bacharev AO, Belichenko OI (1997) Changes in calf muscle performance, energy metabolism, and muscle volume caused by long term stay on space station Mir. Int J Sports Med 18:S308–S309. doi:10.1055/s-2007-972738 PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Jochen Zange
    • 1
    • 3
  • Joachim Mester
    • 2
  • Martina Heer
    • 1
  • Götz Kluge
    • 1
  • Anna-Maria Liphardt
    • 1
    • 2
  1. 1.Institute of Aerospace MedicineDeutsches Zentrum für Luft- und Raumfahrt, German Aerospace Center (DLR e.V.)CologneGermany
  2. 2.Institute of Training Science and Sport InformaticsGerman Sport University CologneCologneGermany
  3. 3.Medical FacultyUniversity of CologneCologneGermany

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