Effects of a multi-nutrient supplement on exercise performance and hormonal responses to resistance exercise
- 1.3k Downloads
The purpose of this study was to determine the influence of a comprehensive multi-component nutritional supplement on performance, hormonal, and metabolic responses to an acute bout of resistance exercise. Nine healthy subjects ingested either Muscle Fuel™ (MF) or a matched placebo (PL) for 7 days. Subjects then reported to the laboratory, ingested the corresponding supplement, and performed two consecutive days of heavy resistance exercise testing with associated blood draws. MF supplementation improved vertical jump (VJ) power output and the number of repetitions performed at 80% of one repetition maximum (1RM). Additionally, MF supplementation potentiated growth hormone (GH), testosterone, and insulin-like growth factor-1 responses to exercise. Concentrations of circulating myoglobin and creatine kinase (CK) were attenuated immediately following resistance exercise during the MF trial, indicating that MF partially mediated some form of exercise-induced muscle tissue damage. In summary MF enhanced performance and hormonal responses associated with an acute bout of resistance exercise. These responses indicate that MF supplementation augments the quality of an acute bout of resistance exercise thereby increasing the endocrine signaling and recovery following heavy resistance exercise.
KeywordsSupplementation Resistance exercise Exercise and muscle damage Hormonal responses to resistance exercise Amino acids
The investigators want to thank a dedicated group of test subjects who made this study possible. In addition, we thank a dedicated group of research assistants and registered dieticians for their help in the dietary control and data collection for this project. This study was supported in part by a grant from AdvoCare Inc.
- Campbell B, Roberts M, Kerksick C, Wilborn C, Marcello B, Taylor L, Nassar E, Leutholtz B, Bowden R, Rasmussen C, Greenwood M, Kreider R (2006) Pharmacokinetics, safety, and effects on exercise performance of l-arginine alpha-ketoglutarate in trained adult men. Nutrition 22:872–881PubMedCrossRefGoogle Scholar
- Kraemer WJ, Fry AC (1995) Strength testing: development and evaluation of methodology. Human Kinetics, Champaign, ILGoogle Scholar
- Kraemer WJ, Spiering BA, Volek JS, Ratamess NA, Sharman MJ, Rubin MR, French DN, Silvestre R, Hatfield DL, Van Heest JL, Vingren JL, Judelson DA, Deschenes MR, Maresh CM (2006) Androgenic responses to resistance exercise: effects of feeding and L-carnitine. Med Sci Sports Exerc 38:1288–1296PubMedCrossRefGoogle Scholar
- Volek JS, Ratamess NA, Rubin MR, Gomez AL, French DN, McGuigan MM, Scheett TP, Sharman MJ, Hakkinen K, Kraemer WJ (2004) The effects of creatine supplementation on muscular performance and body composition responses to short-term resistance training overreaching. Eur J Appl Physiol 91:628–637PubMedCrossRefGoogle Scholar