European Journal of Applied Physiology

, Volume 98, Issue 3, pp 234–241

Creatine supplementation does not enhance submaximal aerobic training adaptations in healthy young men and women

  • T. F. Reardon
  • P. A. Ruell
  • M. A. Fiatarone Singh
  • C. H. Thompson
  • K. B. Rooney
Original Article

Abstract

The benefits of dietary creatine supplementation on muscle performance are generally related to an increase in muscle phosphocreatine content. However, creatine supplementation may benefit endurance sports through increased glycogen re-synthesis following exercise. This study investigated the effect of creatine supplementation on muscle glycogen content, submaximal exercise fuel utilisation and endurance performance following 4 weeks of endurance training. Thirteen healthy, physically active, non-vegetarian subjects volunteered to take part and completed the study. Subjects were supplemented with either creatine monohydrate (CREAT, n = 7) or placebo-maltodextrin (CON, n = 6). Submaximal fuel utilisation and endurance performance were assessed before and after a 4 week endurance training program. Muscle biopsies were also collected before and following training for assessment of muscle creatine and glycogen content. Training increased quadriceps glycogen content to the same degree (∼20%) in both groups (P = 0.04). There was a significant training effect on submaximal fuel utilisation and improved endurance performance. However, there was no significant treatment effect of creatine supplementation. Creatine supplementation does not effect metabolic adaptations to endurance training.

Keywords

Carbohydrate Endurance Glycogen Performance 

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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • T. F. Reardon
    • 1
  • P. A. Ruell
    • 1
  • M. A. Fiatarone Singh
    • 1
    • 2
    • 3
  • C. H. Thompson
    • 4
  • K. B. Rooney
    • 1
  1. 1.School of Exercise and Sport Science, Faculty of Health SciencesUniversity of SydneyLidcombeAustralia
  2. 2.Faculty of MedicineUniversity of SydneySydneyAustralia
  3. 3.Hebrew SeniorLife and John Mayer USDA Human Nutrition Center on Aging at Tufts UniversityBostonUSA
  4. 4.Department of General Medicine, Flinders Medical CentreFlinders University of South AustraliaAdelaideAustralia

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