Association between regional quadriceps oxygenation and blood oxygen saturation during normoxic one-legged dynamic knee extension

  • Kazuki Esaki
  • Takafumi Hamaoka
  • Göran Rådegran
  • Robert Boushel
  • Jim Hansen
  • Toshihito Katsumura
  • Shukoh Haga
  • Masao Mizuno
Original Article

Abstract

It is not clear whether muscle oxygenation (O2-NIRS) measured by near-infrared spectroscopy (NIRS) correlates with femoral venous SO2 (Sfvo2) during normoxic exercise. Therefore, the purpose of this study was to compare physiologically calibrated O2-NIRS with Sfvo2 in subjects performing one-legged dynamic knee extension exercise (1L-KEE). Five healthy male subjects (age 25±2 year, height 177.8±4.8 cm, body weight 67.1 ± 5.0 kg; mean ± SD) performed 1L-KEE at 20, 40, and 60% of peak work rate (WR-peak) each for 4 min. Sfvo2 was measured at rest and during the 3rd minute of each work rate. O2-NIRS was continuously monitored in a proximal region of the vastus lateralis (VL-p), a distal region of VL (VL-d), and a proximal region of the rectus femoris (RF-p). Sfvo2 was 56.0% at rest and decreased to 36.6 at 20% WR-peak, 35.8 at 40% WR-peak, and 31.1 at 60% WR-peak. There was a significant correlation between O2-NIRS and Sfvo2(VL-p: r2 = 0.62, VL-d: r2 = 0.35, RF-p: r2 = 0.62, with a moderate variation among individuals at each site; residual values = 4.83 – 11.75). These data indicate that NIRS measurement provides a reflection of Sfvo2 during 20–60% WR-peak of normoxic 1L-KEE.

Keywords

Near-infrared spectroscopy Muscle oxygenation level Venous blood oxygen saturation 

Notes

Acknowledgements

The support of Prof. Bengt Saltin and the staff of The Copenhagen Muscle Research Centre is greatly appreciated. We also thank all the subjects who participated in this study. This study was supported by part of a grant from the Scientific Research (15200048) by The Ministry of Education, Science, Sports and Culture, Japan.

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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Kazuki Esaki
    • 1
    • 2
  • Takafumi Hamaoka
    • 3
    • 2
  • Göran Rådegran
    • 4
  • Robert Boushel
    • 5
    • 4
  • Jim Hansen
    • 4
  • Toshihito Katsumura
    • 2
  • Shukoh Haga
    • 1
  • Masao Mizuno
    • 6
  1. 1.Institute of Health and Sport SciencesUniversity of TsukubaTsukuba, IbarakiJapan
  2. 2.Department of Preventive Medicine and Public HealthTokyo Medical UniversityTokyoJapan
  3. 3.Department of Sports PerformanceNational Institute of Fitness and Sports in KanoyaKagoshimaJapan
  4. 4.The Copenhagen Muscle Research CenterUniversity of Copenhagen, and RigshospitaletCopenhagenDenmark
  5. 5.Department of Exercise ScienceConcordia UniversityMontrealCanada
  6. 6.Research Unit, Afd. 247Ribe County Hospital EsbjergEsbjergDenmark

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