European Journal of Applied Physiology

, Volume 91, Issue 1, pp 1–6 | Cite as

Sweat lactate response between males with high and low aerobic fitness

  • J. M. GreenEmail author
  • R. C. Pritchett
  • T. R. Crews
  • J. R. McLesterJr.
  • D. C. Tucker
Original Article


Sweat lactate indirectly reflects eccrine gland metabolism. However the potential influence of aerobic fitness on sweat lactate is not well-understood. Six males with high aerobic fitness [peak oxygen consumption (O2peak): 61.6 (2.5) ml·kg−1·min−1] and seven males with low aerobic fitness [O2peak: 41.8 (6.4) ml·kg−1·min−1] completed a maximal exertion cycling trial followed on a different day by 60 min of cycling (60 rev·min−1) in a 30°C wet bulb globe temperature environment. Intensity was individualized at 90% of the ventilatory threshold ( E/O2 increase with no concurrent E/CO2 increase). Sweat samples were collected from the lumbar region every 10 min and analyzed for lactate concentration. Sweat rate (SR) was significantly greater (p<0.05) for subjects with a high [1445 (254) ml·h−1] versus a low [1056 (261) ml·h−1] fitness level. Also, estimated total lactate excretion (SR×mean sweat lactate concentration) was marginally greater (p=0.2) in highly fit males. However, repeated measures ANOVA showed no significant differences (p>0.05) between groups for sweat lactate concentration at any time point. Current results show highly fit (vs. low fitness level) males have a greater sweat rate which is consistent with previous literature. However aerobic fitness and subsequent variations in SR do not appear to influence sweat lactate concentrations in males.


Eccrine glands Lactic acid Sweat composition 



The authors wish to thank Smith and Nephew for their generous donation of the Opsite Wound Dressings used in the current study. Also, appreciation is extended to the Faculty Scholarship Committee at Western Kentucky University for support of the current project.


  1. Ament W, Huizenga JR, Mook GA, Gips CH, Verkerke GJ (1997) Lactate and ammonia concentration in blood and sweat during incremental exercise. Int J Sports Med 18:35–39PubMedGoogle Scholar
  2. Astrand I (1963) Lactate content in sweat. Acta Physiol Scand 58:359–367Google Scholar
  3. Bar-Or O, Lundegren HM, Magnusson LI, Buskirk ER (1968) Distribution of heat-activated sweat glands in obese and lean men and women. Human Biol 40:235–248PubMedGoogle Scholar
  4. Brisson GR, Boisvert P, Peronnet F, Perrault H, Boisvert D, Lafond JS (1991) A simple and disposable sweat collector. Eur J Appl Physiol 50:405–411Google Scholar
  5. Caiozzo VJ, Davis JA, Ellis JF, Azus JL, Vandagriff CA, Prietto CA, McMaster WC (1982) A comparison of gas exchange indices used to detect the anaerobic threshold. J Appl Physiol 53:1184–1189PubMedGoogle Scholar
  6. Fritzsche RG, Coyle EF (2000) Cutaneous blood flow during exercise is higher in endurance-trained humans. J Appl Physiol 88:738–744PubMedGoogle Scholar
  7. Gordon RS Jr, Thompson RH, Muenzer J, Thrasher D (1971) Sweat lactate in man is derived from blood glucose. J Appl Physiol 31:713–716PubMedGoogle Scholar
  8. Green JM, Bishop PA, Muir IH, McLester JR Jr, Heath HE (2000a) Effects of high and low blood lactate concentrations on sweat lactate response. Int J Sports Med 21:1–5PubMedGoogle Scholar
  9. Green JM, Bishop PA, Muir IH, Lopeak RG (2000b) Gender differences in sweat lactate. Eur J Appl Physiol 82:230–235CrossRefPubMedGoogle Scholar
  10. Green JM, Bishop PA, Muir IH, Lopeak RG (2001) Lactate-sweat relationships in younger and middle-aged men. J Aging Phys Act 9:67–77Google Scholar
  11. Jackson AS, Pollock ML (1985) Practical assessment of body composition. Phys Sports Med 13:76–90CrossRefGoogle Scholar
  12. Kuono Y (1956) Human perspiration. Thomas, IllinoisGoogle Scholar
  13. Lamont L (1987) Sweat lactate secretion during exercise in relation to women’s aerobic capacity. J Appl Physiol 62:194–198PubMedGoogle Scholar
  14. Maud PJ, Foster C (eds) (1995) Physiological assessment of human fitness. Human Kinetics, Champaign, Ill.Google Scholar
  15. Mitchell JM, Nadel ER, Stolwijk JAJ (1972) Respiratory weight loss during exercise. J Appl Physiol 32:474–476PubMedGoogle Scholar
  16. Patterson MJ, Galloway SDR, Nimmo MA (2000) Variations in regional sweat composition in normal human males. Exp Physiol, 85:869–875Google Scholar
  17. Sato K (1977) The physiology, pharmacology, and biochemistry of the eccrine sweat gland. Rev Physiol Biochem Pharmacol 79:51–131PubMedGoogle Scholar
  18. Weiner JS, Van Heyningen RE (1952) Observations on lactate content of sweat. J Appl Physiol 4:733–744Google Scholar
  19. Wolfe S, Cage G, Epstein M, Tice L, Miller H, Gordon RS (1970) Metabolic studies of isolated human eccrine sweat glands. J Clin Inv 49:1880–1884Google Scholar
  20. Yukitoshi A, McLellan TM, Shephard RJ (1997) Interactions of physical training and heat acclimation. Sports Med 23:173–210PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • J. M. Green
    • 1
    Email author
  • R. C. Pritchett
    • 1
  • T. R. Crews
    • 1
  • J. R. McLesterJr.
    • 1
  • D. C. Tucker
    • 1
  1. 1.Department of Physical Education and RecreationWestern Kentucky UniversityBowling GreenUSA

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