Phenotypes of individuals affected by airborne chemicals in the general population
- First Online:
To characterise the chemical exposures and symptoms affecting individuals with subsequent adjustments of social life or occupational conditions, and further characterise these severely affected individuals.
All individuals (n = 1,134) who reported symptoms from airborne chemical exposures in a population-based questionnaire study of 6,000 individuals were included and dichotomised according to severity. Logistic regression models were used to characterise the group of severely affected individuals.
Severely affected individuals reported more symptoms and exposures related to symptoms than less severely affected individuals, and the number of symptoms was more predictive for severity than the number of exposures. Most predictive for the severity of reported symptoms were CNS-symptoms other than headache (OR = 3.2, P < 0.001) and exposure to freshly printed papers or magazines (OR = 2.0, P = 0.001).
CNS-symptoms except from headache were a main characteristic of individuals severely affected by common chemical exposures in a general population-based sample.
KeywordsPhenotypes Symptoms Population-based Airborne chemicals Multiple chemical sensitivity Idiopathic environmental intolerance
- Altman DG (1991) Comparing groups—categorical data. In: Practical statistics for medical research. Chapman & Hall, London, pp 229–276Google Scholar
- Carlsson F, Karlson B, Orbaek P, Osterberg K, Ostergren PO (2005) Prevalence of annoyance attributed to electrical equipment and smells in a Swedish population, and relationship with subjective health and daily functioning. Public Health 119:568–577. doi:10.1016/j.puhe.2004.07.011 PubMedCrossRefGoogle Scholar
- Centre for Epidemiology and Research (2003) The New South Wales adult health survey 2002. N S W Public Health Bull 14(Suppl 4):1–148Google Scholar
- Elberling J, Linneberg A, Dirksen A, Johansen JD, Frolund L, Madsen F et al (2005) Mucosal symptoms elicited by fragrance products in a population-based sample in relation to atopy and bronchial hyper-reactivity. Clin Exp Allergy 35:75–81. doi:10.1111/j.1365-2222.2005.02138.x PubMedCrossRefGoogle Scholar