Effects of bioaerosol exposure on work-related symptoms among Swiss sawmill workers

  • S. Rusca
  • N. Charrière
  • P. O. Droz
  • A. Oppliger
Original Article



Exposure to bioaerosols in the occupational environment of sawmills could be associated with a wide range of health effects, in particular respiratory impairment, allergy and organic dust toxic syndrome. The objective of the study was to assess the frequency of medical respiratory and general symptoms and their relation to bioaerosol exposure.


Twelve sawmills in the French part of Switzerland were investigated and the relationship between levels of bioaerosols (wood dust, airborne bacteria, airborne fungi and endotoxins), medical symptoms and impaired lung function was explored. A health questionnaire was distributed to 111 sawmill workers.


The concentration of airborne fungi exceeded the limit recommended by the Swiss National Insurance (SUVA) in the twelve sawmills. This elevated fungi level significantly influenced the occurrence of bronchial syndrome (defined by cough and expectorations). No other health effects (irritations or respiratory effects) could be associated to the measured exposures. We observed that junior workers showed significantly more irritation syndrome (defined by itching/running nose, snoring and itching/red eyes) than senior workers. Lung function tests were not influenced by bioaerosol levels nor dust exposure levels.


Results suggest that occupational exposure to wood dust in a Swiss sawmill does not promote a clinically relevant decline in lung function. However, the occurrence of bronchial syndrome is strongly influenced by airborne fungi levels.


Airborne fungi Endotoxin Lung function Occupational health Sawmill workers Wood dust 



We greatly appreciate the support of all the wood workers who were part of this study. This work was supported by a Swiss National Foundation grant 3200BO-104246 to A.O.


  1. Ahman M, Holmstrom M, Cynkier I, Soderman E (1996) Work related impairment of nasal function in Swedish woodwork teachers. Occup Environ Med 53:112–117PubMedGoogle Scholar
  2. Alwis U, Mandryk J, Hocking AD, Lee J, Mayhew T, Baker W (1999) Dust exposures in the wood processing industry. AIHAJ 60:641–646CrossRefGoogle Scholar
  3. Belin L (1980) Sawmill work and extrinsic allergic alveolitis. Scand J Work Environ Health 6:230PubMedGoogle Scholar
  4. Brooks SM (1981) An approach to patients suspected of having an occupational pulmonary-disease. Clin Chest Med 2:171–178PubMedGoogle Scholar
  5. Carosso A, Ruffino C, Bugiani M (1987) Respiratory-diseases in wood workers. Br J Ind Med 44:53–56PubMedGoogle Scholar
  6. Chanyeung M, Ashley MJ, Corey P, Willson G, Dorken E, Grzybowski S (1978) Respiratory survey of cedar mill workers .1. Prevalence of symptoms and pulmonary-function abnormalities. J Occup Environ Med 20:323–327Google Scholar
  7. Cormier Y, Merlaux A, Duchaine C (2000) Respiratory health impact of working in sawmills in eastern Canada. Arch Environ Health 55:424–430PubMedGoogle Scholar
  8. Dahlqvist M, Johard U, Alexandersson R, Bergstrom B, Ekholm U, Eklund A, Milosevich B, Tornling G, Ulfvarson U (1992) Lung-function and precipitating antibodies in low exposed wood trimmers in Sweden. Am J Ind Med 21:549–559PubMedCrossRefGoogle Scholar
  9. Demers PA, Teschke K, Kennedy SM (1997) What to do about softwood? A review of respiratory effects and recommendations regarding exposure limits. Am J Ind Med 31:385–398PubMedCrossRefGoogle Scholar
  10. Demers PA, Teschke K, Davies HW, Kennedy SM, Leung V (2000) Exposure to dust, resin acids, and monoterpenes in softwood lumber mills. AIHAJ 61:521–528PubMedCrossRefGoogle Scholar
  11. Douwes J, McLean D, Slater T, Pearce N (2001) Asthma and other respiratory symptoms in New Zealand pine processing sawmill workers. Am J Ind Med 39:608–615PubMedCrossRefGoogle Scholar
  12. Douwes J, McLean D, van der Maarl E, Heederik D, Pearce N (2000) Worker exposures to airborne dust, endotoxin and beta(1,3)-glucan in two New Zealand sawmills. Am J Ind Med 38:426–430PubMedCrossRefGoogle Scholar
  13. Duchaine C, Meriaux A, Thorne PS, Cormier Y (2000) Assessment of particulates and bioaerosols in eastern Canadian sawmills. Aihaj 61:727–732PubMedCrossRefGoogle Scholar
  14. Eduard W, Sandven P, Levy F (1994) Exposure and IgG antibodies to mold spores in wood trimmers: exposure–response relationships with respiratory symptoms. Appl Occup Environ Hyg 9:44–48Google Scholar
  15. Halpin DMG, Graneek BJ, Turnerwarwick M, Taylor AJN (1994) Extrinsic allergic alveolitis and asthma in a sawmill worker—case-report and review of the literature. Occup Environ Med 51:160–164PubMedCrossRefGoogle Scholar
  16. Hessel PA, Herbert FA, Melenka LS, Yoshida K, Michaelchuk D, Nakaza M (1995) Lung health in sawmill workers exposed to pine and Spruce. Chest 108:642–646PubMedGoogle Scholar
  17. Holness DL, Sasskortsak AM, Pilger CW, Nethercott JR (1985) Respiratory-function and exposure-effect relationships in wood dust exposed and control workers. J Occup Environ Med 27:501–506Google Scholar
  18. King ME, Mannino DM, Holguin F (2004) Risk factors for asthma incidence—a review of recent prospective evidence. Panminerva Med 46:97–110PubMedGoogle Scholar
  19. Lindberg A, Eriksson B, Larsson LG (2006) Seven year cumulative incidence of COPD in an age-stratified general population sample. Chest 129:879–885PubMedCrossRefGoogle Scholar
  20. Mandryk J, Alwis KU, Hocking AD (1999) Work-related symptoms and dose–response relationships for personal exposures and pulmonary function among woodworkers. Am J Ind Med 35:481–490PubMedCrossRefGoogle Scholar
  21. Mandryk J, Alwis KU, Hocking AD (2000) Effects of personal exposures on pulmonary function and work-related symptoms among sawmill workers. Ann Occup Hyg 44:281–289PubMedGoogle Scholar
  22. Norrish AE, Beasley R, Hodgkinson EJ, Pearce N (1992) A study of New-Zealand wood workers—exposure to wood dust, respiratory symptoms, and suspected cases of occupational asthma. N Z Med J 105:185–187PubMedGoogle Scholar
  23. Oppliger A, Rusca S, Charrière N, VuDuc T, Droz PO (2005) Assessment of bioaerosols and inhalable dust exposure in swiss sawmills. Ann Occup Hyg 49:385–391PubMedCrossRefGoogle Scholar
  24. Pisaniello DL, Tkaczuk MN, Owen N (1992) Occupational wood dust exposures, life-style variables, and respiratory symptoms. J Occup Environ Med 34:788–792CrossRefGoogle Scholar
  25. Rylander R (1997) Airborne (1−>3)-beta-d-glucan and airway disease in a day-care center before and after renovation. Arch Environ Health 52:281–285PubMedCrossRefGoogle Scholar
  26. Rylander R, Peterson Y, Donham KJ (1990) Questionnaire evaluating organic dust exposure. Am J Ind Med 17:121–126PubMedGoogle Scholar
  27. Schlunssen V, Schaumburg I, Taudorf E, Mikkelsen AB, Sigsgaard T (2002) Respiratory symptoms and lung function among Danish woodworkers. J Occup Environ Med 44:82–98PubMedCrossRefGoogle Scholar
  28. Seifert SA, Von Essen S, Jacobitz K, Crouch R, Lintner CP (2003) Organic dust toxic syndrome: a review. J Toxicol-Clin Toxicol 41:185–193PubMedCrossRefGoogle Scholar
  29. Shamssain MH (1992) Pulmonary-function and symptoms in workers exposed to wood dust. Thorax 47:84–87PubMedGoogle Scholar
  30. Siroux V, Pin I, Oryszczyn MP, Le Moual N, Kauffmann F (2000) Relationships of active smoking to asthma and asthma severity in the EGEA study. Eur Resp J 15:470–477CrossRefGoogle Scholar
  31. Teschke K, Marion SA, Vaughan TL, Morgan MS, Camp J (1999) Exposures to wood dust in US industries and occupations, 1979 to 1997. Am J Ind Med 35:581–589PubMedCrossRefGoogle Scholar
  32. Thorn J, Beijer L, Rylander R (1998) Airways inflammation and glucan exposure among household waste collectors. Am J Ind Med 33:463–470PubMedCrossRefGoogle Scholar
  33. Urrutia I, Capelastegui A, Quintana JM, Muniozguren N, Basagana X (2005) Smoking habits, respiratory symptoms andlung function in young adults. Eur J Pub Health 15:160–165CrossRefGoogle Scholar
  34. Vedal S, Chanyeung M, Enarson D, Fera T, Maclean L, Tse KS, Langille R (1986) Symptoms and pulmonary-function in western red cedar workers related to duration of employment and dust exposure. Arch Environ Health 41:179–183PubMedCrossRefGoogle Scholar
  35. Vogelzang PFJ, van der Gulden JWJ, Folgering H, Kolk JJ, Heederik D, Preller L, Tielen MJM, van Schayck CP (1998) Endotoxin exposure as a major determinant of lung function decline in pig farmers. Am J Resp Crit Care Med 157:15–18PubMedGoogle Scholar
  36. Whitehead LW (1982) Health-effects of wood dust—relevance for an occupational standard. AIHAJ 43:674–678CrossRefGoogle Scholar
  37. Wimander K, Belin L (1980) Recognition of allergic alveolitis in the trimming department of a Swedish Sawmill. Eur J Resp Dis 61:163–167Google Scholar

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • S. Rusca
    • 2
  • N. Charrière
    • 1
  • P. O. Droz
    • 1
  • A. Oppliger
    • 1
  1. 1.Institut Universitaire Romand de Santé au Travail, Institute for Work and HealthUniversity of Lausanne and GenevaLausanneSwitzerland
  2. 2.CIMO SA, CPMontheySwitzerland

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