Non-sensitising air pollution at workplaces and adult onset asthma

Original Article

Abstract

Objective

The aim of this study was to elucidate further whether occupational exposure to non-sensitising air pollution at workplaces increases the risk of adult onset asthma.

Methods

One hundred and twenty persons with asthma diagnosed by general practitioners, aged 20–65 years, were compared with 446 referents matched for age and gender and living in the same community as the cases. Information about occupation, exposure to specific allergens, smoking habits, dwellings and atopy was obtained from a postal questionnaire. The subjects' occupations were categorised as clean or polluted, based on the judgement of the referents on their respective occupations.

Results

Three years or more of work in air-polluted workplaces resulted in an odds ratio of 1.7 (95% confidence interval 1.0–2.7). Stratification of the material on smoking habits, gender or atopy did not alter the results, nor did exclusion of subjects exposed to specific allergens of statistical significance in this material, e.g. flour dust. Smoking per se did not bring any risk of asthma. Working in buildings affected by dampness and mould brought a fourfold significant risk.

Conclusion

In this study occupational exposure to unspecific air pollution at workplaces was associated with an increased risk of adult-onset asthma.

Keywords

Dust Building dampness Non-allergic asthma Case–referent study Low-level RADS Exposure matrix 

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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  1. 1.Department of Occupational and Environmental MedicineUniversity HospitalLinköpingSweden

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