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Posterior capsular opacification evaluation through contrast sensitivity defocus curves with two multifocal intraocular lenses of similar material

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Abstract

Purpose

To assess the degree of posterior capsular opacification (PCO) and its influence on contrast sensitivity defocus curve (CSDC) after implantation of two trifocal intraocular lenses (IOLs), Alsafit (AT) and Liberty (L), during a 12-month follow-up. A secondary aim was to evaluate the Nd:YAG capsulotomy rate in a long time.

Methods

Data from 63 subjects, 34 implanted with AT and 29 with L, were retrospectively analyzed for this pilot study. In those eyes without capsulotomy during the first year (n = 58), CSDC at 3 and 12 months after surgery and PCO grading were measured, with additional answering of a visual function questionnaire (VF-14) and a question of general satisfaction. The period after surgery up to capsulotomy or last on-demand visit without Nd:YAG was recorded for survival analysis beyond the 12-month follow-up.

Results

Total area under CSDC (TAUC) between 3 and 12 months decreased from 2.96 to 1.71 for AT (p < 0.05) and from 2.73 to 2.21 (p > 0.05) for L. Of eyes, 51.6, 19.3, and 29% with AT were graded as level 0, 1, and 2 of PCO, while 85.1, 11.1, and 3.7% of eyes with L were graded as level 0, 1, and 2 (p < 0.05). PCO grading was correlated with a decrease of TAUC (ρ =  − 0.27, p = 0.04). Median time to require capsulotomy was 22 months with AT and 30 months with L (p < 0.05).

Conclusions

PCO decreases CSDC in patients with trifocal lenses. Despite using the same hydrophilic material, PCO grading and Nd:YAG capsulotomy rate was higher for AT than for L.

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Authors and Affiliations

  1. Department of Ophthalmology (Qvision), VITHAS Hospital, 04120, Almería, Spain

    Joaquín Fernández, Javier García-Montesinos, Javier Martínez & Manuel Rodríguez-Vallejo

  2. Department of Ophthalmology, Carlos Haya University Regional Hospital, 29010, Málaga, Spain

    Javier García-Montesinos

  3. Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain

    David P. Piñero

  4. Department of Ophthalmology (OFTALMAR), Vithas Medimar International Hospital, Alicante, Spain

    David P. Piñero

Authors
  1. Joaquín Fernández
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  2. Javier García-Montesinos
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  3. Javier Martínez
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  4. David P. Piñero
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  5. Manuel Rodríguez-Vallejo
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Corresponding author

Correspondence to Manuel Rodríguez-Vallejo.

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Ethical approval

All procedures were in accordance of the Ethics Committee of Research, Almería Center, Torrecardenas Hospital Complex, and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.

Conflict of interest

Dr. Fernández is a consultant from Medicontur. Rodriguez-Vallejo M. designed and programmed the Multifocal Lens Analyzer which is distributed through the Apple Store by his own developer account. Other authors have nothing to disclose.

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Fernández, J., García-Montesinos, J., Martínez, J. et al. Posterior capsular opacification evaluation through contrast sensitivity defocus curves with two multifocal intraocular lenses of similar material. Graefes Arch Clin Exp Ophthalmol 259, 2995–3002 (2021). https://doi.org/10.1007/s00417-021-05262-5

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  • DOI: https://doi.org/10.1007/s00417-021-05262-5

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