Preoperative aniseikonia is a prognostic factor for postoperative stereopsis in patients with unilateral epiretinal membrane

Graefe's Archive for Clinical and Experimental Ophthalmology volume 258, pages743–749(2020)Cite this article

Abstract

Purpose

To investigate stereopsis and other visual functions in patients with unilateral epiretinal membrane (ERM) and to identify vision-related parameters affecting stereopsis.

Methods

This prospective study included 63 consecutive patients who were scheduled to undergo vitrectomy for unilateral idiopathic ERM. We examined stereopsis (Titmus Stereo Test, TST; TNO stereotest, TNO), best-corrected visual acuity (BCVA), letter contrast sensitivity, severity of metamorphopsia, and degree of aniseikonia preoperatively and 6 months postoperatively.

Results

Preoperatively, we observed significant correlation between TST scores and other vision-related parameters except severity of metamorphopsia and between TNO score and all the vision-related parameters. Multiple regression analysis showed that preoperative TST and TNO scores were significantly associated with the degree of aniseikonia (both P < 0.01). ERM surgery significantly improved stereopsis, BCVA, contrast sensitivity, and metamorphopsia, but not aniseikonia. Postoperatively, TST was significantly associated with BCVA, and TNO showed association with BCVA and aniseikonia. Postoperative TST and TNO scores showed significant correlation with preoperative aniseikonia (P < 0.005 and P < 0.001, respectively).

Conclusions

Impairment of stereopsis in patients with unilateral ERM was considered to be due to retinally induced aniseikonia. Aniseikonia did not improve by surgery, and preoperative aniseikonia can be a prognostic factor for postoperative stereopsis.

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Author information

Affiliations

  1. Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan

    Fumiki Okamoto, Shohei Morikawa, Yoshimi Sugiura, Sujin Hoshi, Takahiro Hiraoka & Tetsuro Oshika

Authors
  1. Fumiki Okamoto
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  2. Shohei Morikawa
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  3. Yoshimi Sugiura
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  4. Sujin Hoshi
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  5. Takahiro Hiraoka
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  6. Tetsuro Oshika
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Correspondence to Fumiki Okamoto.

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The authors declare that they have no conflicts of interest.

Ethical approval

We conducted this prospective comparative study in accordance with the Declaration of Helsinki and received approval from the institutional review committees of the University of Tsukuba Hospital. Prior to enrollment in the study, all patients provided informed consent after the nature of the study was explained (On line 69–72 of the manuscript).

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Okamoto, F., Morikawa, S., Sugiura, Y. et al. Preoperative aniseikonia is a prognostic factor for postoperative stereopsis in patients with unilateral epiretinal membrane. Graefes Arch Clin Exp Ophthalmol 258, 743–749 (2020). https://doi.org/10.1007/s00417-020-04625-8

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Keywords

  • Aniseikonia
  • Stereopsis
  • Epiretinal membrane
  • Prognostic factor
  • Vitrectomy