Optical coherence tomography angiography assessment of the macular capillary plexus after surgery for macula-off rhegmatogenous retinal detachment
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Macula-involved rhegmatogenous retinal detachment (RRD) is a condition that can cause severe central visual disturbance, even after successful retinal re-attachment. Optical coherence tomography angiography (OCTA) can measure vessel density (VD) in the macular capillary plexus (MCP), both superficially (the SCP) and deeply (the DCP), and can measure the foveal avascular zone (FAZ) in these layers. Previous research used OCTA to evaluate the correlation between the FAZ and visual acuity (VA) in the eyes with macula-off RRD . Here, we extend previous results by including measurements of OCTA-measured VD in both the SCP and DCP, and compared these measurements with other clinical findings, including VA and foveal thickness (FT), in order to investigate in greater detail the significance of vascular changes in the eyes with successfully re-attached macula-off RRD.
Twenty-seven eyes of 27 patients (47.4 ± 16.7 years old) were included. All patients had clinically detectable...
This paper was supported in part by JST grants from the JSPS KAKENHI Grants-in-Aid for Scientific Research (C) (H.K. 17K11445). The funders had no role in design or conduct of the study; collection, management, analysis, or interpretation of the data; preparation, review, or approval of the manuscript; or the decision to submit the manuscript for publication.
Compliance with ethical standards
This study followed the tenets of the Declaration of Helsinki. Informed consent was obtained for all treatments from each patient. The Institutional Review Board of Tohoku University Graduate School of Medicine approved the research for this retrospective study. The principal investigators, Dr. Naoko Yui and Dr. Naoko Aizawa, had full access to all data in the study. They take responsibility for the integrity of the data and the accuracy of the data analysis. No authors have any potential conflicts of interest to disclose.