Response to: Choroidal thickness changes stratified by outcome in real-world treatment of diabetic macular edema
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We thank Călugăru et al. for their interest in our report about the role of the mean baseline subfoveal choroidal thickness (SFCT), as a predictor of outcome in real-world treatment of diabetic macular edema (DME).
The authors considered the following, as possible bias, in our study, (i) about half of the population had past laser history; (ii) different forms of non-proliferative diabetic retinopathy (NPDR) were included; (iii) the eyes that developed proliferative diabetic retinopathy, the eyes that were rescued by laser or switched to steroids were excluded from the follow-up, and (iv) 13 eyes were treated with aflibercept.
Previously, we stated that it is under dispute how choroidal thickness (CT) changes with the NPDR staging, but not with the anti-VEGF use, in any form of NPDR . Supplementary Fig. 2 depicts that differences in CT regarding past laser history were not significant. Outcome calculations were done at...
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