The efficacy of fascial granuloma excision with conjunctival autografting after pterygium surgery
Background and objective
Pterygium has a high recurrence rate after simple excision, and fascial granuloma is one of the common complications of pterygium excision. This study aimed to investigate the treatment for the fascial granuloma.
In this study, the 36 eyes of 36 cases with fascial granuloma after pterygium excision were collected and divided into two groups to receive granuloma excision and conjunctival autografting or simple granuloma excision. The patients in the treatment group containing 20 cases received granuloma excision and conjunctival autografting, while the patients in the control group containing 16 cases received simple granuloma excision.
The pathology examination results showed that all the removed granulomas were inflammatory granulation tissues that without bacterial infection. After 12 months’ follow-up, there was no recurrence of fascia granuloma and pterygium in the treatment group, in which the cure rate was up to 100%. In the control group, 6 cases experienced a recurrence of the granuloma fascia 2~3 weeks after operation; after further granuloma excision and conjunctival autografting, pterygium recurred in 8 cases.
The fascial granuloma excision with conjunctival autografting is effective and safe in treating fascial granuloma after pterygium surgery, which contributes to reducing the recurrence of pterygium.
KeywordsPterygium Fascial granuloma excision Conjunctival autografting
Compliance with ethical standards
The authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
For this type of study formal consent is not required.
- 5.Vorstenbosch J, Gallant-Behm C, Trzeciak A et al (2013) Transgenic mice overexpressing CD109 in the epidermis display decreased inflammation and granulation tissue and improved collagen architecture during wound healing. Wound Repair Regen 21:235–246. https://doi.org/10.1111/wrr.12023 CrossRefPubMedGoogle Scholar
- 6.Yamane T, Nakagami G, Yoshino S et al (2015) Hydrocellular foam dressings promote wound healing associated with decrease in inflammation in rat periwound skin and granulation tissue, compared with hydrocolloid dressings. Biosci Biotechnol Biochem 79:185–189. https://doi.org/10.1080/09168451.2014.968088 CrossRefPubMedGoogle Scholar
- 13.Li J, Zhou DH, Lu LN (2011) Clinical observations of conjunctival autografting combined with mitomycin C in treatment of pterygium. Journal of Shanghai Jiaotong University 31:1102–1104Google Scholar