Morphometric assessment of normal human ciliary body using ultrasound biomicroscopy

Graefe's Archive for Clinical and Experimental Ophthalmology volume 255, pages2437–2442(2017)Cite this article

Abstract

Purpose

To quantitatively assess the biometry of the ciliary body in normal human eyes using ultrasound biomicroscopy.

Methods

We evaluated 85 eyes of 85 normal subjects (35 men and 50 women), whose age ranged from 11 to 86 years (mean ± SD, 56.8 ± 20.4 years). The eyes were assessed along the 3-, 6-, 9-, and 12-o’clock meridians relative to the center of the cornea. Clinical data were collected, including age, axial length, ciliary body length (CBL), ciliary body thickness (CBT), anterior chamber depth, iris root thickness, trabecular–iris angle, and scleral-ciliary process angle. Axial length was measured using A-scan ultrasonography.

Results

CBL and CBT tended to be larger in the superior than in the inferior quadrant, but the differences among the four quadrants were not statistically significant. The average CBL showed a significant positive correlation with the average CBT (r = 0.40, P < 0.001). Average CBL and CBT were significantly correlated with axial length (r = 0.33, P = 0.031; r = 0.46, P < 0.01 respectively). In addition, the average CBL was significantly correlated with anterior chamber depth (r = 0.23, P < 0.05), trabecular-iris angle (r = 0.29, P = 0.01), and scleral-ciliary process angle (r = 0.40, P < 0.001).

Conclusions

Ultrasound biomicroscopic imaging demonstrated that the ciliary body is similar in size in all circumferences, and eyes with longer axial length have an elongated and thicker ciliary body. The values obtained in the present study may serve as standard clinical references.

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Funding

No author has received public or private funding support for this research.

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Affiliations

  1. Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan

    Yoshifumi Okamoto, Fumiki Okamoto & Tetsuro Oshika

  2. Department of Ophthalmology, Ryugasaki Saiseikai General Hospital, Ibaraki, Japan

    Shinichiro Nakano

Authors
  1. Yoshifumi Okamoto
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  2. Fumiki Okamoto
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  3. Shinichiro Nakano
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  4. Tetsuro Oshika
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Contributions

Design of the study (Y.O, F.O., S.N., T.O.); conduct of the study (Y.O., F.O., S.N.); data collection (Y.O.); management, analysis, and interpretation of the data (Y.O., F.O.); preparation of the manuscript (Y.O.); review of the manuscript (T.O.); approval of the manuscript (Y.O., F.O., S.N., T.O.).

Corresponding author

Correspondence to Yoshifumi Okamoto.

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Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Okamoto, Y., Okamoto, F., Nakano, S. et al. Morphometric assessment of normal human ciliary body using ultrasound biomicroscopy. Graefes Arch Clin Exp Ophthalmol 255, 2437–2442 (2017). https://doi.org/10.1007/s00417-017-3809-4

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Keywords

  • Ciliary body
  • Ciliary body length
  • Ciliary body thickness
  • Normal subjects
  • Ultrasound biomicroscopy