Giant premacular bursa: a novel finding of the posterior vitreous in two patients with Stickler syndrome type 1 revealed by swept-source optical coherence tomography

  • Kevin C. Chen
  • Jesse J. Jung
  • Michael EngelbertEmail author
Letter to the Editor

Dear Editor,

Characteristic changes within the retrolental vitreous in Stickler syndrome type 1 (STL1) have been identified with slit lamp biomicroscopy [1]. However, imaging of the posterior vitreous has been lacking, relying only on B-scan ultrasound and time-domain optical coherence tomography (TD-OCT) [2, 3]. Herein, we report the first swept-source optical coherence tomography (SS-OCT) images of the posterior vitreous anatomy in a father and son with genetically-confirmed STL1.

A 12-year-old white boy with a past ocular history significant for STL1 ( COL2A1mutation), high myopia and scleral buckles for bilateral retinal detachments presented for evaluation. Review of systems was negative for hearing loss or joint problems. Family history was positive for STL1 in his father (see case 2). Anterior segment examination was significant for esotropia and retrolental vitreous membranous anomalies. Wide-field Optos photographs revealed vitreous veils and pigmented lattice in both eyes...


Retinal Detachment Cleft Palate High Myopia Scleral Buckle Esotropia 
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This work was supported by a research grant from the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear and Throat Hospital, and The Macula Foundation, Inc. The funding organizations had no role in the design or conduct of this research.

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

The patient/next of kin/guardian has consented to submission of this case report to the journal.


No financial disclosures or proprietary interest


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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Kevin C. Chen
    • 1
  • Jesse J. Jung
    • 1
    • 2
    • 3
    • 4
  • Michael Engelbert
    • 1
    • 2
    • 3
    • 4
    Email author
  1. 1.Department of OphthalmologyNew York University School of MedicineNew YorkUSA
  2. 2.Department of Ophthalmology, Edward S. Harkness Eye InstituteColumbia University College of Physicians and SurgeonsNew YorkUSA
  3. 3.Vitreous-Retina-Macula Consultants of New YorkNew YorkUSA
  4. 4.LuEsther T. Mertz Retinal Research CenterManhattan Eye, Ear and Throat InstituteNew YorkUSA

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