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Calcification of combined hamartoma of the retina and retinal pigment epithelium over 15 years

  • Colleen M. CebullaEmail author
  • Harry W. FlynnJr.
Letter to the Editor
  • 214 Downloads

Dear Editor,

Combined hamartomas of the retina and retinal pigment epithelium consist of thickened, disorganized retina, vascular tortuosity, as well as RPE, and gliotic changes [1, 2]. Despite their congenital nature, little is known about long-term pathologic changes of these lesions; some long-term reports have included 7–15-year data, but have not detailed the lesion and imaging changes in cases beyond 10 years [3, 4]. This report documented one lesion with 15-year follow-up, and demonstrated the prominent calcification of the lesion with spectral domain optical coherence tomography (SD-OCT) and autofluorescence (AF) and color photography.

A 3-year-old healthy white male was examined at Bascom Palmer Eye Institute, and had a grayish, moderately elevated, macular-involving retinal lesion measuring 7.5 × 4.9 mm in the superior temporal posterior pole in the left eye consistent with a combined hamartoma (Fig.  1a). There was surface gliosis of the lesion, which reached the fovea with...

Keywords

Combined hamartoma of the retina and retinal pigment epithelium Spectral domain optical coherence tomography (SD-OCT) Autofluorescence Calcification Osseous metaplasia 

Notes

Acknowledgments

Supported in part by Research to Prevent Blindness, New York, NY and The Ohio State University, Department of Ophthalmology and Visual Science, Havener Eye Institute research fund. We thank Dr. Donald Gass for his care of the patient.

Conflict of interest

The authors declare no conflict of interest.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Ophthalmology and Visual Science, Havener Eye InstituteOhio State UniversityColumbusUSA
  2. 2.Department of Ophthalmology, Bascom Palmer Eye InstituteMiami Miller School of MedicineMiamiUSA

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