Calcification of combined hamartoma of the retina and retinal pigment epithelium over 15 years
Combined hamartomas of the retina and retinal pigment epithelium consist of thickened, disorganized retina, vascular tortuosity, as well as RPE, and gliotic changes [1, 2]. Despite their congenital nature, little is known about long-term pathologic changes of these lesions; some long-term reports have included 7–15-year data, but have not detailed the lesion and imaging changes in cases beyond 10 years [3, 4]. This report documented one lesion with 15-year follow-up, and demonstrated the prominent calcification of the lesion with spectral domain optical coherence tomography (SD-OCT) and autofluorescence (AF) and color photography.
KeywordsCombined hamartoma of the retina and retinal pigment epithelium Spectral domain optical coherence tomography (SD-OCT) Autofluorescence Calcification Osseous metaplasia
Supported in part by Research to Prevent Blindness, New York, NY and The Ohio State University, Department of Ophthalmology and Visual Science, Havener Eye Institute research fund. We thank Dr. Donald Gass for his care of the patient.
Conflict of interest
The authors declare no conflict of interest.
- 1.Gass JD (1997) Stereoscopic atlas of macular disease diagnosis and treatment. Mosby, St Louis, pp 824–835Google Scholar