Femtosecond laser treatment of the crystalline lens: a 1-year study of possible cataractogenesis in minipigs

  • Roland AckermannEmail author
  • Kathleen S. Kunert
  • Robert Kammel
  • Sabine Bischoff
  • Stephanie C. Bühren
  • Harald Schubert
  • Marcus Blum
  • Stefan Nolte
Refractive Surgery



To investigate the long-term stability and possible cataractogenesis after femtosecond laser treatment of the crystalline lens.


The crystalline lenses of ten Göttingen minipigs® underwent femtosecond laser treatment. During a subsequent 1-year follow-up, the pigs were monitored by means of slit-lamp examination of the anterior segment and Scheimpflug imaging of the lens.


No laser-induced cataractogenesis was observed during the 1-year follow-up. The laser pattern showed a stable appearance under all examination devices.


Femtosecond laser treatment seems to be no trigger for cataract formation. Moreover, the long-term stability of the laser pattern makes it suitable for applications such as presbyopia treatment.


Cataract Crystalline lens Femtosecond laser Presbyopia 



This work is supported by the German Federal Ministry of Education and Research (Grant-IDs: 13 N8831, 13 N8835). We are also grateful to Dr. Matthias Reich for his assistance during the preparation of this study.


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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Roland Ackermann
    • 1
    Email author
  • Kathleen S. Kunert
    • 2
  • Robert Kammel
    • 1
  • Sabine Bischoff
    • 3
  • Stephanie C. Bühren
    • 1
  • Harald Schubert
    • 3
  • Marcus Blum
    • 2
  • Stefan Nolte
    • 1
  1. 1.Institute of Applied PhysicsFriedrich-Schiller-Universität JenaJenaGermany
  2. 2.Department of OphthalmologyHELIOS Klinikum Erfurt GmbHErfurtGermany
  3. 3.Institute of Laboratory Animal ScienceFriedrich-Schiller-Universität JenaJenaGermany

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