Titanium back plate for a PMMA keratoprosthesis: clinical outcomes
To compare the rate of retroprosthetic membrane (RPM) formation in Boston Keratoprosthesis (BKPro) with polymethyl methacrylate (PMMA) versus titanium backplates.
Retrospective comparative chart review.
Multicenter study population: a total of 78 eyes with keratoprosthesis implants with either PMMA or titanium backplates were included in the study. To be included in the study, all subjects had to have completed a minimum of 6-month follow-up period. Incidence of RPM development at 6-month postoperative period was noted across the study population. PMMA and titanium backplates were then compared by their rate of association with subsequent RPM.
Twenty-three out of 55 eyes (41.8%) with PMMA backplates and three out of 23 eyes (13.0%) with titanium backplates had developed an RPM at 6 months after implantation. The titanium backplates were associated with significantly less RPM formation than PMMA backplates (p = 0.014, Chi-square test).
Titanium seems to be associated with less RPM formation than PMMA when used as a material for the BKPro back plate.
KeywordsBoston Keratoprosthesis Keratoprosthesis KPro BKPro Retroprosthetic membrane RPM PMMA Titanium
Study was supported by the Keratoprosthesis Fund, Massachusetts Eye and Ear Infirmary.
Conflicts of interest
All authors are full time employees of their listed institutes and otherwise have no financial interest in any companies or products mentioned in the article. Study approved by Institutional Review Board Committees of the individual institutions. Performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki.
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