Fyodorov–Zuev keratoprosthesis implantation: long-term results in patients with multiple failed corneal grafts

  • Alireza Ghaffariyeh
  • Nazafarin Honarpisheh
  • Akbar Karkhaneh
  • Reza Abudi
  • Zinaida Ivanovna Moroz
  • Alireza Peyman
  • Abolhasan Faramarzi
  • Fuad Abasov
Cornea
First Online:
Received:
Revised:
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Abstract

Background

The long term results of the Fyodorov–Zuev keratoprosthesis are presented for ten patients with repeated graft failures.

Methods

The study took place at Dr Khodadoust Eye Hospital. The Fyodorov–Zuev keratoprosthesis was implanted in ten patients with repeated graft failures, including seven patients with old trachoma, two patients with chemical injury, and a patient with thermal injury. The outcome measures were visual acuity, retention, and complications of the keratoprosthesis.

Results

Preoperative best-uncorrected visual acuity (BUVA) ranged from counting fingers to light perception (median: light perception). The keratoprosthesis dramatically improved vision in most patients. Patients retained BUVA of 20/200–20/50 in 50%, 20/60–20/100 in 30%, 20/200 in 10% and 20/400 in 10%. Overall, 90% had 1 year postoperative vision of 20/200 or better. 70% of cases had BUVA of 20/200 or better at the last follow-up (average 52 months). Of ten keratoprosthesis implanted, three have been removed, and as a result, retention rate was 70% during average follow-up of 52 months .The most common postoperative complications were retroprosthetic membrane formation (40%), uveitis (20%), glaucoma (20%), tissue overgrowth (20%), early leakage (20%), late leakage (20%), aseptic necrosis (20%), retinal detachment (10%), endophthalmitis (10%), and granulation tissue growth (10%).

Conclusions

Fyodorov–Zuev keratoprosthesis is an effective means of managing repeated corneal graft failure.

Keywords

Fyodorov–Zuev keratoprosthesis Repeated graft failures Visual recovery Complications 
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Notes

Acknowledgements

The authors are grateful to Prof. Leonid Legkikkh, Prof. Kalinnikov from Svyatoslav N. Fyodorov Eye Microsurgery Research and Technology Complex, Moscow , Prof. Kasparov from Krasnove eye Institute, Moscow, Prof. Konrad Hille from Augenklinik, Klinikum Offenburg, Germany , Prof. Christopher Liu from Sussex Eye Hospital, Brighton, UK , Prof. Claes Dohlman and Prof. Mahnaz Nouri from Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, and Dr Sadollah Puyan from Dr Khodadoust Eye Hospital for their kind cooperation, and we also gratefully acknowledge the Dr Khodadoust Eye Hospital, Shiraz, Iran.

The authors got the Fyodorov–Zuev keratoprosthesis from the S. Fyodorov Eye Microsurgery Complex, Building 59-A, 127486, Beskudnikovskij Blvd, Moscow, Russia. Order Keratoprosthesis #15-09 by calling (495) 485 77 95, sending a request by fax (495) 485 77 95, (495) 905 81 47 or e-mail etp-mntk@mail.ru www.mntk.ru

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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Alireza Ghaffariyeh
    • 1
  • Nazafarin Honarpisheh
    • 1
  • Akbar Karkhaneh
    • 2
  • Reza Abudi
    • 1
  • Zinaida Ivanovna Moroz
    • 3
  • Alireza Peyman
    • 4
  • Abolhasan Faramarzi
    • 5
  • Fuad Abasov
    • 6
  1. 1.Dr. Khodadoust Eye HospitalShirazIran
  2. 2.Science and Research Branch, Biomedical Engineering FacultyIslamic Azad UniversityTehranIran
  3. 3.Svyatoslav N. Fyodorov Eye Microsurgery Research and Technology ComplexMoscowRussia
  4. 4.Ophthalmology DepartmentIsfahan University of Medical Sciences and Health ServicesIsfahanIran
  5. 5.Department of Otolaryngology Head-Neck Surgery, Khalili Eye HospitalShiraz University of Medical SciencesShirazIran
  6. 6.Z.Aliyeva Eye Research InstituteBakuAzerbaijan

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