Noemi Lois and John V. Forrester: Fundus Autofluorescence
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This hardcover book presents on 285 pages current knowledge of fundus autofluorescence and its implementation in clinical practice. The editors Noemi Lois and John V. Forrester have invited 40 well-known experts in the field of fundus autofluorescence to contribute chapters to this book.
This book is divided into two major sections. The first section summarizes basic aspects of fundus autofluorescence. In this part of the book, information on synthesis and degradation and accumulation of lipofuscein, the main pigment originating the autofluorescence signal, is also presented. Furthermore, there are chapters describing imaging techniques, and ways of interpretation and quantifying fundus autofluorescence. In the second section, the implementation of fundus autofluorescence in clinical science and practice is presented, starting with the distribution of autofluorescence in the normal eye, followed by fundus autofluorescence associated with various diseases. The first of these chapters addresses fundus autofluorescence in age-related macular degeneration, a disease where fundus autofluorescence is already frequently used additionally to other imaging techniques to obtain a more accurate diagnosis. Other chapters address fundus autofluorescence in inherited retinal dystrophies, choriodermia, macular holes, and intraocular tumors.
The chapters are overall well-structured, clearly written, and well-referenced. In the second section, all chapters provide principal information of the disease, appearance in fundus autofluorescence and other imaging techniques, value of fundus autofluorescence in the diagnosis and follow-up of the disease, a short summary, and references. A series of images of high quality not only of fundus autofluorescence but also colour fundus photography, fluoresccein angiography and optical coherence tomography underline the text. Appropriate legends explain the pathology presented.
In summary, fundus autofluorescence is a non-invasive new, but becoming more widespread, imaging technique providing important additional information for various disorders of the retina to that provided by standard examination techniques such as fluorescein angiography and optical coherence tomography. In this book, a detailed overview of the field of fundus autofluorescence is presented, of major interest not only for ophthalmologists with special interest in retina. Additionall,y an online access to the complete contents is offered.