Association between foveal photoreceptor status and visual acuity after resolution of diabetic macular edema by pars plana vitrectomy

  • Atsushi Sakamoto
  • Kazuaki Nishijima
  • Mihori Kita
  • Hideyasu Oh
  • Akitaka Tsujikawa
  • Nagahisa Yoshimura
Retinal Disorders

DOI: 10.1007/s00417-009-1107-5

Cite this article as:
Sakamoto, A., Nishijima, K., Kita, M. et al. Graefes Arch Clin Exp Ophthalmol (2009) 247: 1325. doi:10.1007/s00417-009-1107-5

Abstract

Summary

We retrospectively investigated the relationship between the appearance of IS/OS line on OCT images and visual acuity after resolution of DME by vitrectomy. Postoperative visual acuity of eyes with complete IS/OS after resolution of DME was significantly better than that without complete IS/OS, though macular edema was completely resolved in both groups.

Purpose

To evaluate the correlation between photoreceptor layer status following resolution of diabetic macular edema (DME) by pars plana vitrectomy (PPV) and final visual acuity (VA).

Methods

We retrospectively studied a series of 69 eyes from 58 patients with DME who were treated with PPV. Of the 69 eyes, 37 that were examined by optical coherence tomography (OCT) for at least 6 months and that showed a final macular thickness of less than 250 µm were included in this study. We assessed the integrity of the photoreceptor inner and outer segments (IS/OS) line in the fovea, using OCT in relation to their VA and other characteristics.

Results

There were no differences in initial VA or in foveal thickness between eyes with or without complete IS/OS at final observation. However, final VA without complete IS/OS was significantly poorer (P = 0.004). VA had improved by more than 2 lines in eight of ten eyes with complete IS/OS and in ten of 27 eyes without complete IS/OS; the groups differed significantly with regard to this percentage (P = 0.03).

Conclusions

The postoperative photoreceptor status of the fovea is closely related to the final VA after resolution of DME by PPV.

Keywords

Diabetic retinopathy Macular edema Optical coherence tomography Pars plana vitrectomy Photoreceptor layer 

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Atsushi Sakamoto
    • 1
  • Kazuaki Nishijima
    • 1
  • Mihori Kita
    • 1
  • Hideyasu Oh
    • 1
  • Akitaka Tsujikawa
    • 1
  • Nagahisa Yoshimura
    • 1
  1. 1.Department of Ophthalmology and Visual SciencesKyoto University Graduate School of MedicineSakyo-kuJapan

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