Bilateral optic neuropathy and unilateral tonic pupil associated with acute human herpesvirus 6 infection: a case report

  • Isabel M. Oberacher-Velten
  • Jost B. Jonas
  • Anselm Jünemann
  • Barbara Schmidt
Short Communication

Abstract

Background

Human herpesvirus 6 (HHV-6), a widespread virus and causative agent of exanthema subitum in children, has been associated with a number of neurologic disorders including cranial nerve palsies, seizures, encephalitis, meningitis, and multiple sclerosis.

Patient

A 31-year-old man presented with bilateral optic neuropathy, disc edema, and unilateral tonic pupil, which were found to be associated with acute HHV-6 infection. The patient had been suffering from juvenile diabetes for 5 years. One week after onset of intravenous antiviral therapy with foscarnet, disc edema subsided, and tonic pupil reaction was no longer detectable.

Conclusions

HHV-6 infection may play a role as a causative agent in patients with optic neuropathy and tonic pupil.

Keywords

Human herpesvirus 6 Optic neuropathy Disc edema Tonic pupil 

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Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Isabel M. Oberacher-Velten
    • 1
  • Jost B. Jonas
    • 1
    • 2
  • Anselm Jünemann
    • 1
  • Barbara Schmidt
    • 3
  1. 1.Department of Ophthalmology and University Eye HospitalUniversity of Erlangen-NürnbergErlangenGermany
  2. 2.Department of Ophthalmology and University Eye Hospital MannheimUniversity of HeidelbergMannheimGermany
  3. 3.Department of VirologyUniversity of Erlangen-NürnbergErlangenGermany

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