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Reduction of retinal blood flow in high myopia

  • Noriaki Shimada
  • Kyoko Ohno-MatsuiEmail author
  • Seiyo Harino
  • Takeshi Yoshida
  • Kenjiro Yasuzumi
  • Ariko Kojima
  • Kanako Kobayashi
  • Soh Futagami
  • Takashi Tokoro
  • Manabu Mochizuki
Clinical Investigation

Abstract

Purpose

To investigate changes in retinal vessel diameter and blood velocity in high myopia using laser Doppler velocimetry.

Methods

Thirty-nine subjects (39 eyes) were enrolled in the study. The subjects were divided into three groups according to their refractive status; 15 eyes (15 patients) with emmetropia (within ±3.0 diopters), 14 eyes (14 patients) with mild myopia (between −3.0 and −8.0 diopters), and 10 eyes (10 patients) with high myopia (>−8.0 diopters). Patient age was matched between groups. Blood velocity and vessel diameter of the upper or lower temporal retinal artery were measured using laser Doppler velocimetry with an eye-tracking system, and measurements were compared between groups.

Results

The average retinal blood flow and vessel diameter in highly myopic eyes were significantly decreased compared with emmetropic eyes or mild myopic eyes (Mann-Whitney U test, p<0.05). Also, there was significant difference regarding retinal blood flow and vessel diameter between eyes with mild myopia and the other groups. In addition, there was no significant difference in blood velocity between the three groups.

Conclusions

Retinal blood flow was decreased in high myopia, mainly due to the narrowing of the retinal vessel diameter. Impaired retinal blood flow might have a role in the development of chorioretinal atrophy in high myopia.

Keywords

Myopia Refractive Error Blood Velocity Laser Doppler Velocimetry High Myopia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgement

This work was supported in part by research grant 14571659 from the Japanese Ministry of Education, Culture, Sports, Science and Technology

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Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Noriaki Shimada
    • 1
  • Kyoko Ohno-Matsui
    • 1
    Email author
  • Seiyo Harino
    • 2
  • Takeshi Yoshida
    • 1
  • Kenjiro Yasuzumi
    • 1
  • Ariko Kojima
    • 1
  • Kanako Kobayashi
    • 1
  • Soh Futagami
    • 1
  • Takashi Tokoro
    • 1
  • Manabu Mochizuki
    • 1
  1. 1.Department of Ophthalmology and Visual ScienceTokyo Medical and Dental UniversityBunkyo-ku, TokyoJapan
  2. 2.Department of OphthalmologyYodogawa Christian HospitalOsakaJapan

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