High-dose steroid therapy for CNS inflammatory diseases increases INR in patients taking oral vitamin K antagonist
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Stefano Gelibter: acquisition and analysis of data, drafting the manuscript; Mario Orrico, Tommaso Croese, Luca Bosco, Vittorio Martinelli, Francesca Sangalli: acquisition and analysis of data, revising the manuscript; Massimo Filippi: revising the manuscript; study supervision.
Compliance with ethical standards
Conflicts of interest
Stefano Gelibter, Mario Orrico, Tommaso Croese, Luca Bosco, Vittorio Martinelli, and Francesca Sangalli have nothing to disclose. Massimo Filippi is Editor-in-Chief of the Journal of Neurology; received compensation for consulting services and/or speaking activities from Biogen Idec, Merck-Serono, Novartis, and Teva Pharmaceutical Industries; and receives research support from Biogen Idec, Merck-Serono, Novartis, Teva Pharmaceutical Industries, Roche, Italian Ministry of Health, Fondazione Italiana Sclerosi Multipla, and ARiSLA (Fondazione Italiana di Ricerca per la SLA).
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional committee and the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.