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Benign paroxysmal positional vertigo in Meniere’s disease: systematic review and meta-analysis of frequency and clinical characteristics

  • Mansur A. KutlubaevEmail author
  • Ying Xu
  • Jeremy Hornibrook
Review
  • 39 Downloads

Abstract

There is a recognized association of Meniere’s disease (MD) and benign paroxysmal positional vertigo (BPPV). However, the frequency and clinical characteristics of BPPV in MD are unclear. The aim of this review was to determine the mean frequency and clinical features of BPPV in MD. Three databases were searched: MEDLINE, PubMed and Google Academia. Studies reporting the frequency of BPPV in MD were pooled. A total of 4198 references were identified, of which 20 studies were considered eligible. The pooled frequency of BPPV in MD was 14% (95% CI 9–18%). It was 38% (95% CI 26–49%) in longitudinal studies and 8% (95% CI 6–11%) in cross-sectional ones. BPPV comorbid with MD was mostly observed in the ear affected by hydrops, in females, in patients with more advanced disease. Canalolithiasis of the horizontal semicircular canal was more common in patients with BPPV associated with MD than in idiopathic BPPV. BPPV in MD was more prone to recurrence and required more canal repositioning maneuvers.

Keywords

Benign paroxysmal positional vertigo Meniere’s disease Hydrops Otolithiasis Vertigo 

Notes

Compliance with ethical standards

Conflicts of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

References

  1. 1.
    Kim JS, Zee DS (2014) Clinical practice. Benign paroxysmal positional vertigo. N Engl J Med 370:1138–1147.  https://doi.org/10.1056/nejmcp1309481 CrossRefGoogle Scholar
  2. 2.
    Hemenway WG, Lindsay JR (1956) Postural vertigo due to unilateral sudden partial loss of vestibular function. Ann Otol Rhinol Laryngol 65:692–706CrossRefGoogle Scholar
  3. 3.
    Lopez-Escamez JA, Carey J, Chung WH et al (2015) Diagnostic criteria for Meniere’s disease. J Vestib Res 25:1–7.  https://doi.org/10.1007/978-4-431-68111-3_1 Google Scholar
  4. 4.
    Espinosa-Sanchez JM, Lopez-Escamez JA (2016) Menière's disease. Handb Clin Neurol 137:257–277.  https://doi.org/10.1016/b978-0-444-63437-5.00019-4 CrossRefGoogle Scholar
  5. 5.
    Schuknecht HF (1974) Pathology of the ear. Harvard University Press, Cambridge, p 462 (Philadelphia: Lea and Febiger, 1974:469) Google Scholar
  6. 6.
    Gibson WPR (2019) Meniere's disease. Adv Otorhinolaryngol 82:77–86.  https://doi.org/10.1159/000490274 Google Scholar
  7. 7.
    Yamane H, Sunami K, Iguchi H, Sakamoto H, Imoto T, Rask-Andersen H (2012) Assessment of Meniere’s disease from a radiological aspect—saccular otoconia as a cause for Meniere’s disease? Acta Otolaryngol 132:1054–1060.  https://doi.org/10.3109/00016489.2012.680980 CrossRefGoogle Scholar
  8. 8.
    Hornibrook J, Bird P (2017) A new theory for Meniere’s disease: detached saccular otoconia. Otolaryngol Head Neck Surg 156:350–352.  https://doi.org/10.1177/0194599816675843 CrossRefGoogle Scholar
  9. 9.
    Hornibrook J (2018) Saccular otoconia as a cause of Ménière's disease: hypothesis based on two theories. J Laryngol Otol 132(9):771–774.  https://doi.org/10.1017/s0022215118001366 CrossRefGoogle Scholar
  10. 10.
    Karlberg M, Hall K, Quickert N, Hinson J, Halmagyi GM (2000) What inner ear diseases cause benign paroxysmal positional vertigo? Acta Otolaryngol 120:380–385.  https://doi.org/10.1080/000164800750000603 CrossRefGoogle Scholar
  11. 11.
    Balatsouras DG, Ganelis P, Aspris A, Economou NC, Moukos A, Koukoutsis G (2012) Benign paroxysmal positional vertigo associated with Meniere’s disease: epidemiological, pathophysiologic, clinical, and therapeutic aspects. Ann Otol Rhinol Laryngol 121:682–688.  https://doi.org/10.1177/000348941212101011 CrossRefGoogle Scholar
  12. 12.
    Parapella MM (2008) Benign paroxysmal positional vertigo and other vestibular symptoms in Ménière disease. Ear Nose Throat J 87(10):562.  https://doi.org/10.1177/014556130808701006 CrossRefGoogle Scholar
  13. 13.
    Wu ZM, Zhang SZ, Liu XJ, Chen X, Ji F, Chen AT, Yang WY, Han DY (2007) Benign paroxysmal positioning vertigo related to inner ear disorders. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 42(11):821–825.  https://doi.org/10.1159/000095285 Google Scholar
  14. 14.
    Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D et al (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. JAMA 283(15):2008–2012.  https://doi.org/10.1001/jama.283.15.2008 CrossRefGoogle Scholar
  15. 15.
    Moher D, Liberati A, Tetzlaff J, Altman DG, Altman D, Antes G et al (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 6(7):e1000097.  https://doi.org/10.1371/journal.pmed.1000097 CrossRefGoogle Scholar
  16. 16.
    Gananca CF, Caovilla HH, Gazzola JM, Gananca MM, Gananca FF (2007) Epley’s maneuver in benign paroxysmal positional vertigo associated with Meniere’s disease. Braz J Otorhinolaryngol 73:506–512.  https://doi.org/10.1016/s1808-8694(15)30102-6 CrossRefGoogle Scholar
  17. 17.
    Proctor LR (2000) Results of serial vestibular testing in unilateral Ménière's disease. Am J Otol 21(4):552–558Google Scholar
  18. 18.
    Handa PR, Kuhn AM, Cunha F, Schaffleln R, Ganança FF (2005) Quality of life in patients with benign paroxysmal positional vertigo and/or Ménière's disease. Braz J Otorhinolaryngol 71(6):776–782.  https://doi.org/10.1016/s1808-8694(15)31248-9 CrossRefGoogle Scholar
  19. 19.
    Hughes CA, Proctor L (1997) Benign paroxysmal positional vertigo. Laryngoscope 107(5):607–613.  https://doi.org/10.1097/00005537-199705000-00010 CrossRefGoogle Scholar
  20. 20.
    Lee NH, Ban JH, Lee KC, Kim SM (2010) Benign paroxysmal positional vertigo secondary to inner ear disease. Otolaryngol Head Neck Surg 143(3):413–417.  https://doi.org/10.1016/j.otohns.2010.06.905 CrossRefGoogle Scholar
  21. 21.
    Motasaddi-Zarandi M, Nemati Sh, Panahi R, Akbari M (2015) Benign paroxysmal positional vertigo incidence in Meniere’s disease: is Meniere's disease a predisposing factor? Casp J Neurol Sci 1(1):7–11.  https://doi.org/10.18869/acadpub.cjns.1.1.7 CrossRefGoogle Scholar
  22. 22.
    Gross EM, Ress BD, Viirre ES, Nelson JR, Harris JP (2000) Intractable benign paroxysmal positional vertigo in patients with Meniere's disease. Laryngoscope 110(4):655–659.  https://doi.org/10.1097/00005537-200004000-00022 CrossRefGoogle Scholar
  23. 23.
    Inagaki T, Yukawa K, Ichimura A, Hagiwara A, Ogawa Y, Kitajima N et al (2008) Clinical study of BPPV-like symptom associated with inner ear disease. Equilib Res 67:18–23.  https://doi.org/10.3757/jser.67.18 CrossRefGoogle Scholar
  24. 24.
    Li P, Zeng XL, Li YQ, Zhang GH, Ye J (2010) The clinical characteristics of the benign paroxysmal positional vertigo associated with Meniere's disease. Zhonghua Yi Xue Za Zhi 90(27):1921–1923Google Scholar
  25. 25.
    Pal'chun VT, Mel'nikov OA, Levina YV, Guseva AL (2018) The peculiar features of the clinical course of Meniere's disease associated with benign paroxysmal positional vertigo. Vestn Otorinolaringol 83(1):32–35.  https://doi.org/10.17116/otorino201883132-35 CrossRefGoogle Scholar
  26. 26.
    Luryi AL, Lawrence J, Bojrab D, LaRouere M, Babu S, Hong R, Zappia J, Sargent E, Chan E, Naumann IC, Schutt CA (2018) Patient, disease, and outcome characteristics of benign paroxysmal positional vertigo with and without Meniere's disease. Acta Otolaryngol 138(10):893–897.  https://doi.org/10.1080/00016489.2018.1484566 CrossRefGoogle Scholar
  27. 27.
    Guo X, Wang Q, Mei X, Zhang Z, Yang X, He P (2015) Benign paroxysmal positional vertigo associated with Meniere's disease: analysis of 36 cases. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 29(10):925–927Google Scholar
  28. 28.
    Yetişer S (2017) Co-existence of benign paroxysmal positional vertigo and Meniere's syndrome. J Int Adv Otol 13(1):65–68.  https://doi.org/10.5152/iao.2016.2906 CrossRefGoogle Scholar
  29. 29.
    Rossi Izquierdo M, Soto Varela A, Santos Pérez S, Labella Caballero T (2009) Association between endolymphatic hydrops and benign paroxysmal positional vertigo: coincidence or causality? Acta Otorrinolaringol Esp 60(4):234–237.  https://doi.org/10.1016/j.otorri.2009.02.003 CrossRefGoogle Scholar
  30. 30.
    van Esch BF, van Benthem PP, van der Zaag-Loonen HJ, Bruintjes TD (2016) Two common second causes of dizziness in patients with Ménière's disease. Otol Neurotol 37(10):1620–1624.  https://doi.org/10.1097/mao.0000000000001215 CrossRefGoogle Scholar
  31. 31.
    Taura A, Funabiki K, Ohgita H, Ogino E, Torii H, Matsunaga M, Ito J (2014) One-third of vertiginous episodes during the follow-up period are caused by benign paroxysmal positional vertigo in patients with Meniere's disease. Acta Otolaryngol 134(11):1140–1145.  https://doi.org/10.3109/00016489.2014.936624 CrossRefGoogle Scholar
  32. 32.
    Zhu MC, Zhou F, Tan GJ, Wang M, Yu F, Wang HT, Huang LF, Liang ZJ (2016) Clinical analysis of benign paroxysmal positional vertigo associated with Meniere's disease. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 30(20):1615–1619.  https://doi.org/10.13201/j.issn.1001-1781.2016.20.009 Google Scholar
  33. 33.
    Dornhoffer JL, Colvin GB (2000) Benign paroxysmal positional vertigo and canalith repositioning: clinical correlations. Am J Otol 21(2):230–233.  https://doi.org/10.1016/s0196-0709(00)80014-9 CrossRefGoogle Scholar
  34. 34.
    Ralli G, Nota G, Lamberti A, Gallo A (2003) La malattia di Ménière e la vertigine parossistica posizionale. Arq Otorrinolaringol 7(1):32–37Google Scholar
  35. 35.
    Committee on Hearing and Equilibrium (1995) Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Meniere’s disease. Otolaryngol Head Neck Surg 113:181–185.  https://doi.org/10.1016/s0194-5998(95)70102-8 CrossRefGoogle Scholar
  36. 36.
    Takeda N, Nishiike S, Kitahara T, Kubo T, Ogino H, Koizuka I (1997) Clinical features and utricular dysfunction in patients with benign paroxysmal positional vertigo. Nihon Jibiinkoka Gakkai Kaiho 100:449–456.  https://doi.org/10.3950/jibiinkoka.100.449 CrossRefGoogle Scholar
  37. 37.
    Manzari L (2008) Enlarged vestibular aqueduct (EVA) related with recurrent benign paroxysmal positional vertigo (BPPV). Med Hypotheses 70(1):61–65.  https://doi.org/10.1016/j.mehy.2007.04.032 CrossRefGoogle Scholar
  38. 38.
    Phillips JS, Prinsley PR (2009) A unified hypothesis for vestibular dysfunction? Otolaryngol Head Neck Surg 140:477–479.  https://doi.org/10.1016/j.otohns.2008.12.028 CrossRefGoogle Scholar
  39. 39.
    Jahn AF (2017) Benign positional vertigo and endolymphatic hydrops: what is the connection? J Laryngol Otol 131(8):658–660.  https://doi.org/10.1017/S002221511700130X CrossRefGoogle Scholar
  40. 40.
    Morita N, Cureoglu S, Nomiya S, Nomiya R, Joglekar SS, Harada T, Paparella MM (2009) Potential cause of positional vertigo in Ménière's disease. Otol Neurotol 30(7):956–960.  https://doi.org/10.1097/MAO.0b013e3181b24368 CrossRefGoogle Scholar
  41. 41.
    Gacek RR (2009) Meniere’s disease is a viral neuropathy. ORL Otorhinolaryngol Relat Spec 2:78–86.  https://doi.org/10.1159/000189783 CrossRefGoogle Scholar
  42. 42.
    Bartels LJ, Danner CJ, Allen KP (2016) Office-based Meniere’s disease management. Oper Tech Otolaryngol 27:225–234.  https://doi.org/10.1016/j.otot.2016.10.009 CrossRefGoogle Scholar
  43. 43.
    Jeong SH (2019) Kim JS (2019) Impaired calcium metabolism in benign paroxysmal positional vertigo: a topical review. J Neurol Phys Ther 43:S37–S41.  https://doi.org/10.1097/NPT.0000000000000273 CrossRefGoogle Scholar
  44. 44.
    Becker-Bense S, Wittmann C (2019) Dieterich M (2019) Balanced sex distribution in patients with Menière's disease. J Neurol 78:89.  https://doi.org/10.1007/s00415-019-09301-4 Google Scholar
  45. 45.
    Gürkov R, Flatz W, Ertl-Wagner B, Krause E (2013) Endolymphatic hydrops in the horizontal semicircular canal: a morphologic correlate for canal paresis in Ménière's disease. Laryngoscope 123(2):503–506.  https://doi.org/10.1002/lary.23395 CrossRefGoogle Scholar
  46. 46.
    Parnes LS, McClure JA (1992) Free-floating endolymph particles: new operative finding during posterior semicircular canal occlusion. Laryngoscope 102:1988–1992.  https://doi.org/10.1288/00005537-199209000-00006 CrossRefGoogle Scholar
  47. 47.
    Brandt T, Steddin S (1993) Current view of the mechanism of benign paroxysmal positioning vertigo: cupulolithisiasis or canalithiasis? J Vestib Res 3:373–382Google Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of NeurologyBashkir State Medical UniversityUfaRussia
  2. 2.Department of NeurologyG.G. Kuvatov Republican Clinical HospitalUfaRussia
  3. 3.Sydney Medical SchoolUniversity of SydneySydneyAustralia
  4. 4.The George Institute for Global Health, Faculty of MedicineUniversity of New South WalesCamperdownAustralia
  5. 5.Department of Otolaryngology-Head and Neck Surgery and AudiologyChristchurch HospitalChristchurchNew Zealand

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