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Can verapamil be effective in controlling vertigo and headache attacks in vestibular migraine accompanied with Meniere’s disease? A preliminary study

  • Isa Kaya
  • Sevinc Eraslan
  • Ceyda Tarhan
  • Cem Bilgen
  • Tayfun Kirazli
  • Figen Gokcay
  • Hale Karapolat
  • Nese CelebisoyEmail author
Letter to the Editors
  • 19 Downloads

Dear Sirs,

Several studies have pointed to an association between migraine, vestibular migraine (VM) and Meniere’s Disease (MD) [1, 2, 3, 4, 5, 6, 7]. Though the underlying link is not clear they seem to be parts of a broad spectrum disorder [5] and can share a common genetic basis to confer susceptibility [2]. “VM/MD overlapping syndrome” diagnosis has been proposed for patients presenting with simultaneous symptoms/signs of VM and MD [7].

Depending on clinical similarities with episodic ataxia type 2 and familial hemiplegic migraine, voltage-dependent calcium channel gene (CACNA1A) mutations have been searched in patients with VM, but could not be identified [8, 9]. Potassium channel mutations [10] and the role of aquaporins in inner ear water homeostasis [11] have been speculated in MD pathophysiology.

Based on these speculations, we tried to analyze the efficacy of verapamil, a calcium channel blocker in controlling vertigo and headache attacks of patients with VM associated with...

Notes

Compliance with ethical standards

Conflicts of interest

No conflict of interest.

Ethical standards

All procedures were performed in accordance with the ethical standards stated in the Declaration of Helsinki and its later amendments.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of OtolaryngologyEge University Medical SchoolIzmirTurkey
  2. 2.Department of NeurologyEge University Medical SchoolIzmirTurkey
  3. 3.Department of OtolaryngologyIğdır State HospitalIğdırTurkey
  4. 4.Department of Physical Therapy and RehabilitationEge University Medical SchoolIzmirTurkey

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