Ictal downbeat nystagmus in bilateral Meniere’s disease
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Pure or predominantly vertical nystagmus mostly indicates a lesion involving the central vestibular structures, and downbeat nystagmus is usually observed in inferior cerebellar lesions . Herein, we describe ictal downbeat nystagmus in a patient with bilateral MD.
Dr. SUL analyzed and interpreted the data, and wrote the manuscript. Drs. HJK, ESL and JYC analyzed and interpreted the data, and revised the manuscript. Dr. JSK designed and conceptualized the study, interpreted the data, and revised the manuscript.
Compliance with ethical standards
This study was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (no. NRF-2016R1D1A1B04935568).
Conflicts of interest
Drs. S. U. Lee, I. S. Lee, H. J. Kim and Choi report no disclosures. Dr. J. S. Kim serves as an associate editor of Frontiers in Neuro-otology and on the editorial boards of the Journal of Korean Society of Clinical Neurophysiology, Journal of Clinical Neurology, Frontiers in Neuro-ophthalmology, Journal of Neuro-ophthalmology, Journal of Vestibular Research, Journal of Neurology, and Medicine.
This study followed the tenets of the Declaration of Helsinki, and was performed according to the guidelines of Institutional Review Board of Seoul National University Bundang Hospital (B-1109/135-106).
Video. During an attack of Meniere’s disease, the patient shows spontaneous nystagmus beating downward, leftward, and counter-clockwise (from the patient’s perspective) without fixation. Then the spontaneous nystagmus reverses its horizontal and torsional directions into rightward and clockwise while the downbeat component remained unchanged. (WMV 18075 kb)