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Journal of Neurology

, Volume 262, Issue 2, pp 316–325 | Cite as

Compensatory eye and head movements of patients with homonymous hemianopia in the naturalistic setting of a driving simulation

  • Markus BahnemannEmail author
  • Johanna Hamel
  • Sophie De Beukelaer
  • Sven Ohl
  • Stefanie Kehrer
  • Heinrich Audebert
  • Antje Kraft
  • Stephan A. Brandt
Original Communication

Abstract

Homonymous hemianopia (HH) is a frequent deficit resulting from lesions to post-chiasmal brain structures with a significant negative impact on activities of daily living. To address the question how patients with HH may compensate their visual field defect in a naturalistic environment, we performed a driving simulation experiment and quantitatively analyzed both eye and head movements using a head-mounted pupil camera. 14 patients with HH and 14 matched healthy control subjects participated in the study. Based on the detection performance of dynamically moving obstacles, which appeared unexpectedly along the sides of the road track, we divided the patient group into a high- and a low-performance group. Then, we compared parameters of eye and head movements between the two patient groups and the matched healthy control group to identify those which mediate successful detection of potentially hazardous objects. Differences in detection rates could not be explained by demographic variables or the extent of the visual field defect. Instead, high performance of patients with HH in the naturalistic setting of our driving simulation depended on an adapted visual exploratory behavior characterized by a relative increase in the amplitude and a corresponding increase in the peak velocity of saccades, widening horizontally the distribution of eye movements, and by a shift of the overall distribution of saccades into the blind hemifield. The result of the group comparison analyses was confirmed by a subsequent stepwise regression analysis which identified the horizontal spread of eye movements as single factor predicting the detection of hazardous objects.

Keywords

Homonymous hemianopia Stroke Driving simulation Eye and head movements Visual exploratory behavior Compensation 

Notes

Acknowledgments

The study received funding from the Federal Ministry of Education (BMBF) via the grant CSB (01 EO 0801). The Center for Stroke Research Berlin (CSB) is an integrated research and treatment center. We thank the EUWAX Stiftung for additional financial support.

Conflicts of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Supplementary material

415_2014_7554_MOESM1_ESM.pdf (167 kb)
Supplementary material 1 (PDF 166 kb)

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Markus Bahnemann
    • 1
    • 2
    Email author
  • Johanna Hamel
    • 3
  • Sophie De Beukelaer
    • 1
  • Sven Ohl
    • 4
  • Stefanie Kehrer
    • 1
  • Heinrich Audebert
    • 5
    • 6
  • Antje Kraft
    • 1
    • 7
  • Stephan A. Brandt
    • 1
  1. 1.Department of NeurologyCharité Campus Mitte, Charité UniversitätsmedizinBerlinGermany
  2. 2.Department of PsychiatrySchlosspark-ClinicBerlinGermany
  3. 3.Department of NeurologyUniversity of RochesterRochesterUSA
  4. 4.Berlin School of Mind and BrainHumboldt-Universität zu BerlinBerlinGermany
  5. 5.Department of NeurologyCharité Campus Benjamin Franklin, Charité UniversitätsmedizinBerlinGermany
  6. 6.Center for Stroke Research Berlin (CSB)Charité UniversitätsmedizinBerlinGermany
  7. 7.Clinical Research Unit, Berlin Institute of HealthCharité Campus Mitte, Charité UniversitätsmedizinBerlinGermany

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