Journal of Neurology

, Volume 261, Issue 5, pp 1031–1036

Parkinson’s disease: recent advances

Neurological Update


While a curative treatment for Parkinson’s disease remains elusive, our understanding of disease mechanisms as well as preclinical and pre-motor early manifestations has improved greatly over the past years. An agent with proven disease modifying properties has not yet been identified but symptomatic treatment options for affected patients have improved. For patients with motor complications, this includes invasive approaches such as deep brain stimulation and continuous device-aided drug delivery. The many facets of non-motor problems patients are faced with have finally been fully recognized and have become the target of treatment trials, as have been non-pharmacological approaches.


Parkinson’s disease Symptomatic treatment Disease mechanism 

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Neurology, Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative DisordersDonauspital/Danube HospitalViennaAustria

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