Journal of Neurology

, Volume 261, Issue 2, pp 300–308 | Cite as

Selective peripheral denervation: comparison with pallidal stimulation and literature review

  • Maria Fiorella Contarino
  • Pepijn Van Den Munckhof
  • Marina A. J. Tijssen
  • Rob M. A. de Bie
  • D. Andries Bosch
  • P. Richard Schuurman
  • Johannes D. Speelman
Original Communication

Abstract

Patients with cervical dystonia who are non-responders to Botulinum toxin qualify for surgery. Selective peripheral denervation (Bertrand’s procedure, SPD) and deep brain stimulation of the globus pallidus (GPi-DBS) are available surgical options. Although peripheral denervation has potential advantages over DBS, the latter is nowadays more commonly performed. We describe the long-term outcome of selective peripheral denervation as compared with GPi-DBS, along with the findings of literature review. Twenty patients with selective peripheral denervation and 15 with GPi-DBS were included. Tsui scale, a visual analogue scale, and the global outcome score of the Toronto Western Spasmodic Torticollis Rating Scale were used to define a “combined global surgical outcome”. The “combined global surgical outcome” for patients with selective peripheral denervation or pallidal stimulation was respectively “bad” for 65 and 13.3 %, “fair-to-good” for 30 and 26.7 %, and “marked” improvement for 5 and 60 % (p < 0.001). Improvement on visual analogue scale (p < 0.002), global outcome score (p < 0.002), and Tsui score (p < 0.000) was larger for the pallidal stimulation group. Seventy-five percent of patients with selective peripheral denervation and 60 % of patients with pallidal stimulation reported side effects. Seven patients with selective peripheral denervation successively underwent GPi-DBS, with a further significant improvement in the Tsui score (−48.6 ± 17.4 %). GPi-DBS is to be preferred to selective peripheral denervation for the treatment of cervical dystonia because it produces larger benefit, even if it can have more potentially severe complications. GPi-DBS is also a valid alternative in case of failure of SPD.

Keywords

Cervical dystonia Selective peripheral denervation Bertrand’s procedure Deep brain stimulation Globus pallidus 

Supplementary material

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Supplementary material 1 (DOC 27 kb)
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Supplementary material 3 (DOC 41 kb)
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Supplementary material 4 (DOCX 19 kb)

References

  1. 1.
    Brans JW, Lindeboom R, Snoek JW, Zwarts MJ, van Weerden TW, Brunt ER, van Hilten JJ, van der Kamp W, Prins MH, Speelman JD (1996) Botulinum toxin versus trihexyphenidyl in cervical dystonia: a prospective, randomized, double-blind controlled trial. Neurology 46:1066–1072CrossRefPubMedGoogle Scholar
  2. 2.
    Benecke R, Moore P, Dressler D, Naumann M (2003) Cervical and axial dystonia. In: Moore P, Naumann M (eds) Handbook of botulinum toxin treatment. Wiley-Blackwell, OxfordGoogle Scholar
  3. 3.
    Bertrand CM (1993) Selective peripheral denervation for spasmodic torticollis: surgical technique, results, and observations in 260 cases. Surg Neurol 40:96–103CrossRefPubMedGoogle Scholar
  4. 4.
    Chen X, Ma A, Liang J, Ji S, Pei S (2000) Selective denervation and resection of cervical muscles in the treatment of spasmodic torticollis: long-term follow-up results in 207 cases. Stereotact Funct Neurosurg 75:96–102CrossRefPubMedGoogle Scholar
  5. 5.
    Munchau A, Palmer JD, Dressler D, O’Sullivan JD, Tsang KL, Jahanshahi M, Quinn NP, Lees AJ, Bhatia KP (2001) Prospective study of selective peripheral denervation for botulinum-toxin resistant patients with cervical dystonia. Brain 124:769–783CrossRefPubMedGoogle Scholar
  6. 6.
    Kiss ZH, Doig-Beyaert K, Eliasziw M, Tsui J, Haffenden A, Suchowersky O (2007) The Canadian multicentre study of deep brain stimulation for cervical dystonia. Brain 130:2879–2886CrossRefPubMedGoogle Scholar
  7. 7.
    Odekerken VJ, van LT, Staal MJ, Mosch A, Hoffmann CF, Nijssen PC, Beute GN, van Vugt JP, Lenders MW, Contarino MF, Mink MS, Bour LJ, van den Munckhof P, Schmand BA, de Haan RJ, Schuurman PR, de Bie RM (2013) Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson’s disease (NSTAPS study): a randomised controlled trial. Lancet Neurol 12:37–44CrossRefPubMedGoogle Scholar
  8. 8.
    Contarino MF, Foncke EM, Cath DC, Schuurman PR, Speelman JD, Tijssen MA (2011) Effect of pallidal deep brain stimulation on psychiatric symptoms in myoclonus-dystonia due to epsilon-sarcoglycan mutations. Arch Neurol 68:1087–1088CrossRefPubMedGoogle Scholar
  9. 9.
    Tsui JK, Eisen A, Stoessl AJ, Calne S, Calne DB (1986) Double-blind study of botulinum toxin in spasmodic torticollis. Lancet 2:245–247CrossRefPubMedGoogle Scholar
  10. 10.
    Consky ES, Lang AE (1994) Clinical assessments of patients with cervical dystonia. In: Jankovic J, Hallett M (eds) Therapy with botulinum toxin. Marcel Dekker, New York, pp 211–237Google Scholar
  11. 11.
    Capelle HH, Blahak C, Schrader C, Baezner H, Hariz MI, Bergenheim T, Krauss JK (2012) Bilateral deep brain stimulation for cervical dystonia in patients with previous peripheral surgery. Mov Disord 27:301–304CrossRefPubMedGoogle Scholar
  12. 12.
    Huh R, Han IB, Chung M, Chung S (2010) Comparison of treatment results between selective peripheral denervation and deep brain stimulation in patients with cervical dystonia. Stereotact Funct Neurosurg 88:234–238CrossRefPubMedGoogle Scholar
  13. 13.
    The National Institute for Clinical excellence (2004) Selective peripheral denervation of cervical dystoniaGoogle Scholar
  14. 14.
    Albanese A, Barnes MP, Bhatia KP, Fernandez-Alvarez E, Filippini G, Gasser T, Krauss JK, Newton A, Rektor I, Savoiardo M, Valls-Sole J (2006) A systematic review on the diagnosis and treatment of primary (idiopathic) dystonia and dystonia plus syndromes: report of an EFNS/MDS-ES task force. Eur J Neurol 13:433–444CrossRefPubMedGoogle Scholar
  15. 15.
    Albanese A, Asmus F, Bhatia KP, Elia AE, Elibol B, Filippini G, Gasser T, Krauss JK, Nardocci N, Newton A, Valls-Sole J (2011) EFNS guidelines on diagnosis and treatment of primary dystonias. Eur J Neurol 18:5–18CrossRefPubMedGoogle Scholar
  16. 16.
    Speelman JD, Contarino MF, Schuurman PR, Tijssen MA, de Bie RM (2010) Deep brain stimulation for dystonia: patient selection and outcomes. Eur J Neurol 17(Suppl 1):102–106CrossRefPubMedGoogle Scholar
  17. 17.
    Taira T, Hori T (2003) A novel denervation procedure for idiopathic cervical dystonia. Stereotact Funct Neurosurg 80:92–95CrossRefPubMedGoogle Scholar
  18. 18.
    Ford B, Louis ED, Greene P, Fahn S (1998) Outcome of selective ramisectomy for botulinum toxin resistant torticollis. J Neurol Neurosurg Psychiatry 65:472–478PubMedCentralCrossRefPubMedGoogle Scholar
  19. 19.
    Meyer CH (2001) Outcome of selective peripheral denervation for cervical dystonia. Stereotact Funct Neurosurg 77:44–47CrossRefPubMedGoogle Scholar
  20. 20.
    Braun V, Richter HP (2002) Selective peripheral denervation for spasmodic torticollis: 13-year experience with 155 patients. J Neurosurg 97:207–212PubMedGoogle Scholar
  21. 21.
    Cohen-Gadol AA, Ahlskog JE, Matsumoto JY, Swenson MA, McClelland RL, Davis DH (2003) Selective peripheral denervation for the treatment of intractable spasmodic torticollis: experience with 168 patients at the mayo clinic. J Neurosurg 98:1247–1254CrossRefPubMedGoogle Scholar
  22. 22.
    Dauer WT, Burke RE, Greene P, Fahn S (1998) Current concepts on the clinical features, aetiology and management of idiopathic cervical dystonia. Brain 121(Pt 4):547–560CrossRefPubMedGoogle Scholar
  23. 23.
    Walsh RA, Sidiropoulos C, Lozano AM, Hodaie M, Poon YY, Fallis M, Moro E (2013) Bilateral pallidal stimulation in cervical dystonia: blinded evidence of benefit beyond 5 years. Brain 136:761–769CrossRefPubMedGoogle Scholar
  24. 24.
    Taira T, Kobayashi T, Takahashi K, Hori T (2002) A new denervation procedure for idiopathic cervical dystonia. J Neurosurg 97:201–206PubMedGoogle Scholar
  25. 25.
    Munchau A, Good CD, McGowan S, Quinn NP, Palmer JD, Bhatia KP (2001) Prospective study of swallowing function in patients with cervical dystonia undergoing selective peripheral denervation. J Neurol Neurosurg Psychiatry 71:67–72PubMedCentralCrossRefPubMedGoogle Scholar
  26. 26.
    Lobato EB, Black S, De SH (1997) Venous air embolism and selective denervation for torticollis. Anesth Analg 84:551–553PubMedGoogle Scholar
  27. 27.
    Yianni J, Nandi D, Shad A, Bain P, Gregory R, Aziz T (2004) Increased risk of lead fracture and migration in dystonia compared with other movement disorders following deep brain stimulation. J Clin Neurosci 11:243–245CrossRefPubMedGoogle Scholar
  28. 28.
    Kleiner-Fisman G, Herzog J, Fisman DN, Tamma F, Lyons KE, Pahwa R, Lang AE, Deuschl G (2006) Subthalamic nucleus deep brain stimulation: summary and meta-analysis of outcomes. Mov Disord 21(Suppl 14):S290–S304CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Maria Fiorella Contarino
    • 1
    • 3
  • Pepijn Van Den Munckhof
    • 2
  • Marina A. J. Tijssen
    • 1
  • Rob M. A. de Bie
    • 1
  • D. Andries Bosch
    • 2
  • P. Richard Schuurman
    • 2
  • Johannes D. Speelman
    • 1
  1. 1.Department of Neurology/Clinical Neurophysiology, Academic Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands
  2. 2.Department of Neurosurgery, Academic Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands
  3. 3.Department of NeurologyHaga Ziekenhuis Teaching HospitalThe HagueThe Netherlands

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