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Falling too Fahr

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References

  1. 1.

    Stolze H, Klebe S, Zechlin C, Baecker C, Friege L, Deuschl G (2004) Falls in frequent neurological diseases—prevalence, risk factors and aetiology. J Neurol 251(1):79–84. doi:10.1007/s00415-004-0276-8

  2. 2.

    Rubenstein LZ, Josephson KR (2002) The epidemiology of falls and syncope. Clin Geriatr Med 18(2):141–158. doi:10.1016/S0749-0690(02)00002-2

  3. 3.

    Thijs RD, Bloem BR, van Dijk JG (2009) Falls, faints, fits and funny turns. J Neurol 256(2):155–167. doi:10.1007/s00415-009-0108-y

  4. 4.

    Weiss-Guillet EM, Takala J, Jakob SM (2003) Diagnosis and management of electrolyte emergencies. Best Pract Res Clin Endocrinol Metab 17(4):623–651. doi:10.1016/S1521-690X(03)00056-3

  5. 5.

    Morgante L, Trimarchi F, Benvenga S (2002) Fahr’s disease. Lancet 359(9308):759. doi:10.1016/S0140-6736(02)07878-9

  6. 6.

    Bastepe M (2008) The GNAS locus and pseudohypoparathyroidism. Adv Exp Med Biol 626:27–40. doi:10.1159/000083895

  7. 7.

    Mantovani G, Spada A (2006) Mutations in the Gs alpha gene causing hormone resistance. Best Pract Res Clin Endocrinol Metab 20(4):501–513. doi:10.1016/j.beem.2006.09.001

  8. 8.

    Mantovani G, de Sanctis L, Barbieri AM, Elli FM, Bollati V, Vaira V, Labarile P, Bondioni S, Peverelli E, Lania AG, Beck-Peccoz P, Spada A (2010) Pseudohypoparathyroidism and GNAS epigenetic defects: clinical evaluation of albright hereditary osteodystrophy and molecular analysis in 40 patients. J Clin Endocrinol Metab 95(2):651–658. doi:10.1210/jc.2009-0176

  9. 9.

    Manyam BV, Walters AS, Narla KR (2001) Bilateral striopallidodentate calcinosis: clinical characteristics of patients seen in a registry. Mov Disord 16(2):258–264. doi:10.1002/mds.1049

  10. 10.

    Preusser M, Kitzwoegerer M, Budka H, Brugger S (2007) Bilateral striopallidodentate calcification (Fahr’s syndrome) and multiple system atrophy in a patient with longstanding hypoparathyroidism. Neuropathology 27(5):453–456. doi:10.1111/j.1440-1789.2007.00790.x

  11. 11.

    Forstl H, Krumm B, Eden S, Kohlmeyer K (1992) Neurological disorders in 166 patients with basal ganglia calcification: a statistical evaluation. J Neurol 239(1):36–38. doi:10.1007/BF00839209

  12. 12.

    Benke T, Karner E, Seppi K, Delazer M, Marksteiner J, Donnemiller E (2004) Subacute dementia and imaging correlates in a case of Fahr’s disease. J Neurol Neurosurg Psychiatry 75(8):1163–1165

  13. 13.

    McKeon A, Vaughan C, Delanty N (2006) Seizure versus syncope. Lancet Neurol 5(2):171–180. doi:10.1016/S1474-4422(06)70350-7

  14. 14.

    Williams A, Liddle D, Abraham V (2011) Tetany: a diagnostic dilemma. J Anaesthesiol Clin Pharmacol 27(3):393–394. doi:10.4103/0970-9185.83691

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Conflicts of interest

The authors declare that they have no conflicts of interest.

Author information

Correspondence to Arianna Merlini.

Additional information

A. Merlini, L. Peruzzotti-Jametti, and M. Bacigaluppi contributed equally to this work.

Electronic supplementary material

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Supplementary material 1 Online Resource 1 Signs of latent tetany: a positive Chvostek’s sign (twitching of facial musculature) is elicited by tapping the cheek over the path of the facial nerve, 2 cm anterior the earlobe before the zygomatic process. A positive Trousseau’s sign, more specific for latent tetany, is observed with the occurrence of a painful carpal spasm after inflating a sphygmomanometer above the systolic pressure for 3 min. (MPG 15445 kb)

Supplementary material 1 Online Resource 1 Signs of latent tetany: a positive Chvostek’s sign (twitching of facial musculature) is elicited by tapping the cheek over the path of the facial nerve, 2 cm anterior the earlobe before the zygomatic process. A positive Trousseau’s sign, more specific for latent tetany, is observed with the occurrence of a painful carpal spasm after inflating a sphygmomanometer above the systolic pressure for 3 min. (MPG 15445 kb)

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Merlini, A., Peruzzotti-Jametti, L., Bacigaluppi, M. et al. Falling too Fahr. J Neurol 259, 1483–1484 (2012). https://doi.org/10.1007/s00415-012-6411-z

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Keywords

  • Calcium Gluconate
  • Guanine Nucleotide Binding Protein
  • Pseudohypoparathyroidism
  • STX16 Gene
  • Cardiac Syncope