Hashimoto’s encephalopathy mimicking spinocerebellar ataxia
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A 39-year-old man was admitted for complaints of worsening gait difficulty, weakness and dysarthria. His symptoms had developed 17 months earlier with unsteadiness of gait. Subsequently, he gradually developed difficulties in handwriting, weakness and dysarthria. His symptoms were considered as spinocerebellar ataxia in a local hospital and treated with CoQ10, and vitamins B1 and B12. No improvement was observed. His disability accelerated 2 weeks prior to admission. There is no family history of cerebellar symptoms.
Physical examination revealed palpable thyroid gland. Neurological examination showed normal mental status, right central facial weakness, lingual fasciculations, brisk jaw jerk, hyperactive gag reflex and scanning dysarthria. Strength of left upper and right limbs was 4/5 with bilateral palmomental reflexes and right Babinski signs. Focal dystonia was observed in the right hand. He was only able to walk several steps, with broad-based, ataxic gait. Marked...
KeywordsThyroiditis CoQ10 Cerebellar Ataxia Spinocerebellar Ataxia Autoimmune Thyroiditis
This work was supported by the grants from the National Science Foundation of China (No. 30900478, 30973207), The New-Star of Science and Technology supported by Beijing Metropolis (No. 2010B053) and Beijing Natural Science Foundation (No. 7102072).
Conflict of interest
The authors declare that they have no conflict of interest.
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