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Journal of Neurology

, Volume 257, Issue 10, pp 1770–1773 | Cite as

Recent advances in spinal cord neurology

  • Volker Dietz
Medical Progress in the Journal of Neurology

Abstract

This short review summarizes developments and achievements made during the last few years in spinal neurology and includes all relevant papers published in the Journal of Neurology during this time. A focus of the review concerns the debate about the significance of translational medicine in spinal cord injury with the introduction of new drugs directed to achieve some spinal cord repairs.

Keywords

Spinal cord repair Myelopathy Babinski sign Neuroplasticity Spinal cord ischemia 

References

  1. 1.
    Dietz V (2008) Ready for human spinal cord repair? Brain 131(Pt.9):2240–2242CrossRefPubMedGoogle Scholar
  2. 2.
    Wyndaele JJ (2009) Research related to spinal cord management is international. Spinal Cord 47(12):839–840CrossRefPubMedGoogle Scholar
  3. 3.
    Debette S et al (2009) Long-term outcome of acute and subacute myelopathies. J Neurol 256(6):980–988CrossRefPubMedGoogle Scholar
  4. 4.
    Leep Hunderfund AN, Wijdicks EF (2009) Intramedullary spinal cord hemorrhage (hematomyelia). Rev Neurol Dis 6(2):E54–E61PubMedGoogle Scholar
  5. 5.
    Petersen JA, Schubert M, Dietz V (2010) The occurrence of the Babinski sign in complete spinal cord injury. J Neurol 257(1):38–43CrossRefPubMedGoogle Scholar
  6. 6.
    Cheng MY et al (2009) Concomitant spinal cord and vertebral body infarction is highly associated with aortic pathology: a clinical and magnetic resonance imaging study. J Neurol 256(9):1418–1426CrossRefPubMedGoogle Scholar
  7. 7.
    Ota K et al (2009) 18F-FDG PET successfully detects spinal cord sarcoidosis. J Neurol 256(11):1943–1946CrossRefPubMedGoogle Scholar
  8. 8.
    Rath JJ, Ronday HK, Wirtz PW (2010) Acute transverse myelitis in psoriatic arthritis. J Neurol 257(3):457–458CrossRefPubMedGoogle Scholar
  9. 9.
    Eger K et al (2010) Beevor’s sign in facioscapulohumeral muscular dystrophy: an old sign with new implications. J Neurol 257(3):436–438CrossRefPubMedGoogle Scholar
  10. 10.
    Taniguchi A et al (2010) Painful neck on rotation: diagnostic significance for crowned dens syndrome. J Neurol 257(1):132–135CrossRefPubMedGoogle Scholar
  11. 11.
    Matis GK, Birbilis TA (2009) Erythropoietin in spinal cord injury. Eur Spine J 18(3):314–323CrossRefPubMedGoogle Scholar
  12. 12.
    Dietz V (2008) Body weight supported gait training: from laboratory to clinical setting. Brain Res Bull 76(5):459–463CrossRefPubMedGoogle Scholar
  13. 13.
    Jakob W et al (2009) Difficulty of elderly SCI subjects to translate motor recovery—“body function”—into daily living activities. J Neurotrauma 26(11):2037–2044CrossRefPubMedGoogle Scholar
  14. 14.
    Riener R et al (2010) Locomotor training in subjects with sensori-motor deficits: an overview of the robotic gait orthosis Lokomat. J Healthc Eng 1(2):197–216CrossRefGoogle Scholar
  15. 15.
    Heetla HW et al (2009) The incidence and management of tolerance in intrathecal baclofen therapy. Spinal Cord 47(10):751–756CrossRefPubMedGoogle Scholar
  16. 16.
    Barnett SC, Chang L (2004) Olfactory ensheathing cells and CNS repair: going solo or in need of a friend? Trends Neurosci 27(1):54–60CrossRefPubMedGoogle Scholar
  17. 17.
    Ramon-Cueto A et al (2000) Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheathing glia. Neuron 25(2):425–435CrossRefPubMedGoogle Scholar
  18. 18.
    Chhabra HS et al (2009) Autologous olfactory mucosal transplant in chronic spinal cord injury: an Indian Pilot Study. Spinal Cord 47(12):887–895CrossRefPubMedGoogle Scholar
  19. 19.
    Dobkin BH, Curt A, Guest J (2006) Cellular transplants in China: observational study from the largest human experiment in chronic spinal cord injury. Neurorehabil Neural Repair 20(1):5–13CrossRefPubMedGoogle Scholar
  20. 20.
    Mackay-Sim A et al (2008) Autologous olfactory ensheathing cell transplantation in human paraplegia: a 3-year clinical trial. Brain 131(Pt 9):2376–2386CrossRefPubMedGoogle Scholar
  21. 21.
    Lima C et al (2010) Olfactory mucosal autografts and rehabilitation for chronic traumatic spinal cord injury. Neurorehabil Neural Repair 24(1):10–22CrossRefPubMedGoogle Scholar
  22. 22.
    Dietz V, Curt A (2006) Neurological aspects of spinal-cord repair: promises and challenges. Lancet Neurol 5(8):688–694CrossRefPubMedGoogle Scholar
  23. 23.
    Curt A et al (2008) Recovery from a spinal cord injury: significance of compensation, neural plasticity, and repair. J Neurotrauma 25(6):677–685CrossRefPubMedGoogle Scholar
  24. 24.
    Collazos-Castro JE et al (2005) Motoneuron loss associated with chronic locomotion impairments after spinal cord contusion in the rat. J Neurotrauma 22(5):544–558CrossRefPubMedGoogle Scholar
  25. 25.
    Dietz V et al (2009) Changes in spinal reflex and locomotor activity after a complete spinal cord injury: a common mechanism? Brain 132(Pt 8):2196–2205CrossRefPubMedGoogle Scholar
  26. 26.
    Dietz V, Muller R (2004) Degradation of neuronal function following a spinal cord injury: mechanisms and countermeasures. Brain 127(Pt 10):2221–2231CrossRefPubMedGoogle Scholar
  27. 27.
    Guest JD, Hiester ED, Bunge RP (2005) Demyelination and Schwann cell responses adjacent to injury epicenter cavities following chronic human spinal cord injury. Exp Neurol 192(2):384–393CrossRefPubMedGoogle Scholar
  28. 28.
    Klapka N et al (2005) Suppression of fibrous scarring in spinal cord injury of rat promotes long-distance regeneration of corticospinal tract axons, rescue of primary motoneurons in somatosensory cortex and significant functional recovery. Eur J Neurosci 22(12):3047–3058CrossRefPubMedGoogle Scholar
  29. 29.
    Wirz M et al (2010) Outcome after incomplete spinal cord injury: central cord versus Brown-Sequard syndrome. Spinal Cord 48(5):407–414CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  1. 1.Spinal Cord Injury CenterBalgrist University HospitalZürichSwitzerland

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