Journal of Neurology

, Volume 257, Issue 12, pp 2094–2096 | Cite as

Unilateral cerebral hemisphere oedema as a peri-ictal phenomenon

  • Camille CarrollEmail author
  • Konrad Krolikowski
  • William Mukonoweshuro
  • Jonathan Jones
  • C. Oliver Hanemann
Letter to the Editors

Dear Sirs,

Focal peri-ictal abnormalities on cerebral imaging are well described [1], most commonly mimicking tumours [2, 5]. More extensive abnormalities resembling cerebral ischaemia are more rarely described. Here we describe a case of extensive peri-ictal cerebral oedema.

A 37 year-old man with a known craniopharyngioma and secondary epilepsy presented following a cluster of tonic-clonic seizures occurring over the course of a day. At the time of admission he was experiencing generalised tonic-clonic seizures every 10 min. He was apyrexial and normotensive. Neurological examination showed right-sided hemiparesis, right hemianopia and dysphasia. His white blood cell count and C reactive protein were normal. Treatment with phenytoin and lorazepam resulted in resolution of his seizures.

He had been diagnosed with craniopharyngioma at the age of 20 when he presented with a 4-year history of partial seizures manifesting as vacant episodes or right arm focal motor jerks. MRI scan at the...


Apparent Diffusion Coefficient Status Epilepticus Topiramate Diffusion Weighted Imaging Partial Seizure 
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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Camille Carroll
    • 1
    • 2
    Email author
  • Konrad Krolikowski
    • 2
  • William Mukonoweshuro
    • 3
  • Jonathan Jones
    • 3
  • C. Oliver Hanemann
    • 1
    • 2
  1. 1.Department of Clinical NeurobiologyPeninsula Medical SchoolPlymouthUK
  2. 2.Department of NeurologyPlymouth Hospitals NHS TrustPlymouthUK
  3. 3.Department of NeuroradiologyPlymouth Hospitals NHS TrustPlymouthUK

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