Journal of Neurology

, Volume 257, Issue 11, pp 1899–1908

Stenting for the treatment of high-grade intracranial stenoses

  • S. Lanfranconi
  • A. Bersano
  • V. Branca
  • E. Ballabio
  • M. Isalberti
  • R. Papa
  • L. Candelise
Original Communication


To date, evidence to recommend endovascular treatment in patients with intracranial stenoses is lacking. Recently, the introduction of self-expanding stents (Wingspan Stent System) aroused considerable expectations in their employ for stroke prevention. We report a single-center experience of percutaneous transluminal angioplasty and stenting in a series of consecutive patients with intracranial stenoses and compare the safety and performance of balloon-mounted stents versus self-expanding stent systems (Wingspan). Thirty-four patients with 39 severe (>70%) intracranial stenoses were treated during a 6-year period. An independent stroke neurologist collected data about intra and periprocedural complications and short-term outcome. We considered as endpoint measures (1) any 30-day stroke or death (2) any major 30-day complication and (3) procedure technical success. Technical success was achieved in all patients. No vessel dissection or ruptures were observed. The 30-day stroke/death rate was 17.9%. Five ischemic strokes in the territory of treated vessels and two intracranial hemorrhages occurred respectively within 24 h and 5 days after endovascular treatment. Three (17.6%) patients of Wingspan treated group and four (18.2%) of the patients treated with different stent systems had unfavorable outcome. Our study confirms that endovascular treatment can be performed with a high technical success rate, even though the safety of these devices has still to be demonstrated.


Intracranial stenosis Stroke Secondary prevention Stents Angioplasty 


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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • S. Lanfranconi
    • 1
    • 2
  • A. Bersano
    • 1
    • 2
  • V. Branca
    • 3
  • E. Ballabio
    • 1
    • 2
  • M. Isalberti
    • 3
  • R. Papa
    • 3
  • L. Candelise
    • 1
    • 2
  1. 1.Centro Dino FerrariUniversità degli Studi di MilanoMilanItaly
  2. 2.Neurology UnitFondazione IRCCS Cà Granda, Ospedale Maggiore PoliclinicoMilanItaly
  3. 3.Department of Diagnostic and Interventional NeuroradiologyFondazione IRCCS Cà Granda, Ospedale Maggiore PoliclinicoMilanItaly

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