Journal of Neurology

, Volume 257, Issue 4, pp 669–671 | Cite as

Amnestic syndrome due to meningovascular neurosyphilis

  • H. Kearney
  • P. Mallon
  • E. Kavanagh
  • L. Lawler
  • P. Kelly
  • K. O’Rourke
Letter to the editors


In recent years, the human immunodeficiency virus (HIV) pandemic has been accompanied by an increasing incidence of syphilis, particularly among at-risk groups [1,2]. However, the broad range of neurological symptoms attributable to neurosyphilis can render the diagnosis difficult. We describe a hitherto unreported presentation of meningovascular neurosyphilis in a HIV-infected patient.

A 29 year-old woman was brought to hospital in August 2009 having been found wandering the streets of Dublin in a confused state. She was noted to be both alert and co-operative, but disorientated in time and place. The Rivermead Behavioural Memory Test (RBMT) demonstrated significant memory impairment involving episodic and prospective memory, and both immediate and delayed recall of visual and spatial information. Reading, writing and naming were normal. Retrograde memory was intact. She was able to recognize family members. Clinical examination including bedside visual field examination did not...


Human Immunodeficiency Virus Magnetic Resonance Angiography Syphilis Prospective Memory Abacavir 
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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • H. Kearney
    • 1
  • P. Mallon
    • 2
    • 4
  • E. Kavanagh
    • 3
  • L. Lawler
    • 3
  • P. Kelly
    • 1
  • K. O’Rourke
    • 1
    • 5
  1. 1.Neurovascular Clinical Science UnitMater Misericordiae University HospitalDublinIreland
  2. 2.Department of Infectious DiseasesMater Misericordiae University HospitalDublinIreland
  3. 3.Department of RadiologyMater Misericordiae University HospitalDublinIreland
  4. 4.School of Medicine and Medical SciencesUniversity College DublinDublinIreland
  5. 5.Dublin Neurological InstituteDublin 7Ireland

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