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Journal of Neurology

, 256:834 | Cite as

Bifocal extradural cortical stimulation-induced recovery of consciousness in the permanent post-traumatic vegetative state

  • Sergio Canavero
  • Barbara Massa-Micon
  • Franco Cauda
  • Elisa Montanaro
Letter to the Editors

To the Editor:

The chance of recovery from vegetative state (VS) 1 year after traumatic brain injury (TBI) is close to zero, i.e., it is permanent, PVS [5, 14]. Deep brain stimulation (DBS) of the midbrain or thalamus failed to improve awareness in PVS patients [15]. Yet, imaging studies suggest the potential for cognitive processing in a subset of patients and potentially recruitable cortical regions [6, 7, 8, 9, 11]. Isolated thalamocortical “island” circuits may be working in PVS [6, 7, 8, 9, 11]. We now find that bifocal, extradural cortical stimulation (b-ECS), a very safe minimally invasive surgical method [2, 3, 4], can restore conscious contents in the PVS. The present result differs from recent reports of an improvement of the minimally conscious state by DBS [13]: it is known that PVS and the MCS are different physiological entities, with large-scale “higher order” cortical activation on functional neuroimaging in MCS, normally not observed in PVS patients, a much better...

Keywords

Deep Brain Stimulation Encephalomalacia Visual Pursuit Decompressive Hemicraniectomy Simple Order 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Sergio Canavero
    • 1
    • 2
  • Barbara Massa-Micon
    • 1
    • 2
  • Franco Cauda
    • 1
    • 2
  • Elisa Montanaro
    • 2
  1. 1.Turin Advanced Neuromodulation Group (TANG)TurinItaly
  2. 2.TurinItaly

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