Journal of Neurology

, Volume 255, Supplement 4, pp 30–31

Deep brain stimulation for parkinsonian gait disorders


DOI: 10.1007/s00415-008-4005-6

Cite this article as:
Lozano, A.M. & Snyder, B.J. J Neurol (2008) 255(Suppl 4): 30. doi:10.1007/s00415-008-4005-6


The cardinal motor manifestation of Parkinson’s disease (PD) is being treated with greater and greater efficacy with both newer medications as well as both subthalamic nucleus (STN) and globus pallidus internus (GPI) deep brain stimulation (DBS). The burden of disease is shifting towards the non-dopaminergic disease manifestations including gait and posture. Based on evidence in the literature and in animal models, recent trials are underway to examine the effects of pedunculopontine nucleus DBS on the treatment of parkinsonian gait disorder. We review the rationale behind this treatment and the status of the current trials.

Key words

Parkinsonian gait disorders Deep brain stimulation Pedunculopontine nucleus 

Copyright information

© Springer 2008

Authors and Affiliations

  1. 1.Division of NeurosurgeryToronto Western Hospital, University of Toronto, UHNToronto, (ON)Canada

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