Cognitive dysfunctions in multiple sclerosis – a “multiple disconnection syndrome”?

Journal of Neurology volume 254, pages II18–II21 (2007)Cite this article

An Erratum to this article was published on 01 February 2008

Abstract

After giving a brief overview of the cognitive core deficit in multiple sclerosis (MS), pros and cons of considering the clinical characteristics as a form of ‘subcortical dementia’ are discussed. By comparing the neuropsychological descriptions of MS patients as given in the literature to other neurological diseases which are also associated with neuropsychological deficiencies, we propose the term ‘multiple disconnection syndrome’ to describe the variety of neuropsychological deficits encountered in MS.

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Author information

Affiliations

  1. Dept. of neuropsychology and behavioural neurology, University Clinic of Neurology, Bochum-Langendreer, Germany

    Pasquale Calabrese

  2. Dept. of Cognitive neuroscience, University of Basel, Switzerland

    Iris Katharina Penner

  3. Dept. of Neuropsychology and behavioral neurology, Ruhr-University Bochum, In der Schornau 23–25, 44892, Bochum, Germany

    Pasquale Calabrese

Authors
  1. Pasquale Calabrese
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  2. Iris Katharina Penner
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Corresponding author

Correspondence to Pasquale Calabrese.

Additional information

An erratum to this article is available at http://dx.doi.org/10.1007/s00415-008-0901-z.

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Calabrese, P., Penner, I.K. Cognitive dysfunctions in multiple sclerosis – a “multiple disconnection syndrome”?. J Neurol 254, II18–II21 (2007). https://doi.org/10.1007/s00415-007-2006-5

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Key words

  • multiple sclerosis
  • neuropsychology
  • cognition
  • disconnection syndrome