Journal of Neurology

, Volume 253, Supplement 1, pp i3–i9 | Cite as

Autonomic dysfunction in multiple sclerosis

  • Carl-Albrecht HaenschEmail author
  • Johannes Jörg


Multiple sclerosis (MS) is the most frequent chronic neurological disease affecting young persons in developed countries. MS is, however, considered as a secondary cause, of central origin, for autonomic dysfunction. The most common autonomic symptoms in MS are disorders of micturation, impotence, sudomotor and gastrointestinal disturbances, orthostatic intolerance as well as sleep disorders. The majority of the patients suffer at some period of the disease from lower urinary tract symptoms and sexual dysfunction.Awareness and treatment of these conditions is vital to improving health and quality of life in patients with MS. The increased understanding of the pathophysiological mechanisms in autonomic dysfunction in MS, along with technological and pharmaceutical developments has advanced our ability to treat the multiple aspects complicating autonomic failure in MS.

Key words

autonomic dysfunction multiple sclerosis bladder dysfunction sleep gastrointestinal disturbances 


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Copyright information

© Steinkopff-Verlag 2006

Authors and Affiliations

  1. 1.Dept. of.NeurologyHELIOS Klinikum WuppertalWuppertalGermany

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