Acute motor axonal neuropathy presenting with bowel, bladder, and erectile dysfunction
- 85 Downloads
Sirs: Whereas cardiovascular dysfunction occurs in up to 60% of Guillain-Barré syndrome (GBS) patients [1, 2], pelvic organ dysfunction is less common (bladder, 25% ; bowel, 15% [4, 5]). According to subtypes of GBS, heart rate and plasma noradrenaline concentration were elevated in classical GBS [acute inflammatory demyelinating polyneuropathy (AIDP)] (n=7) (overactivity) but not in axonal GBS [acute motor axonal neuropathy (AMAN)] (n=8) , whereas bladder dysfunction was noted in 21% of AIDP (n=24) but in 50% of AMAN (n=4) (mostly underactivity) , presumably reflecting autonomic organ vulnerability among these variants. We recently had a case of AMAN presenting with bowel, bladder, and erectile dysfunction that has rarely been reported in this variant.
KeywordsErectile Dysfunction Nerve Conduction Study Urapidil Bowel Dysfunction Colonic Transit Time
- 5.Lobrano A, Blanchard K, Abell TL, Minocha A, Boone W, Wyatt-Ashmead J, Fratkin J, Subramony C, Wee A Jr, Di Nardo G, Barbara G, Stanghellini V, De Giorgio R (2006) Postinfectious gastroparesis related to autonomic failure: a case report. Neurogastroenterol Motil 18:162–167PubMedCrossRefGoogle Scholar
- 11.Rosen R, Bennet A, Ferguson D, Hirsh M, Padma-Nathan H, Wyllie M (2001) Standards for clinical trials in erectile dysfunction: research designs and outcomes assessment. In: Jardin A, Wagner G, Khoury S, Giuliano F, Padma-Nathan H, Rosen R (eds) Erectile dysfunction. (1st International Consultation on Erectile Dysfunction). Plymbridge Distributors Ltd., Plymouth, UK, pp 649–677Google Scholar