Frequency of current utilisation of complementary and alternative medicine by patients with multiple sclerosis

Journal of Neurology volume 253, pages 1331–1336 (2006)Cite this article

Abstract

Objective

The purpose of the study was to examine the frequency and characteristics of complementary and alternative medicine (CAM) use among patients with multiple sclerosis (MS).

Method

In order to collect sociodemographic and disease related variables as well as aspects of CAM utilisation 254 MS patients were examined with an interview. The investigation was completed by data of the neurological examination.

Results

At the time of investigation 67.3% of the MS patients reported that they were currently using one or more CAMs. Overall, most of the overall utilized therapies (90.6%) were chosen as a complement and 9.4% as an alternative therapy. Users of complementary medicine were more severely affected by the MS than non-users and had a longer duration of illness. No sociodemographic differences were found between users and non-users. When evaluating the efficacy of CAM, patients reported improvement in 67.1%, no influence in 32.3% and worsening in 0.6% of the cases. 3.7% of the CAM therapies were accompanied by minor side effects.

Conclusions

Since MS patients are frequently using CAM despite the absence of clinically proven efficacy and appraise it positively, further research on the motivation for utilisation and on objective effects of CAM are needed.

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References

  1. 1.

    Apel A, Klauer T and Zettl UK (2006 Jan 02) Stress and progression in multiple sclerosis. Fortschr Neurol Psychiatr 74:Epub ahead of print

    Article  Google Scholar 

  2. 2.

    Astin JA (1998) Why patients use alternative medicine. JAMA 279:1548–1553

    PubMed  CAS  Article  Google Scholar 

  3. 3.

    Berkman CS, Pignotti MG, Cavallo PF, Holland NJ (1999) Use of alternative treatments by people with multiple sclerosis. Neurorehabil Neural Repair 13:243–254

    Google Scholar 

  4. 4.

    Bocker B, Bühring M, Bühring M, Dietze L, Eickmann F, Elies M, et al. (2000) Dictionary for naturopathy. de Gruyter, Berlin

    Google Scholar 

  5. 5.

    Bowling AC (2001) Alternative medicine and multiple sclerosis. Demos, New York

    Google Scholar 

  6. 6.

    Bowling AC, Stewart TM (2003) Current complementary and alternative therapies for multiple sclerosis. Curr Treat Options Neurol 5:55–68

    PubMed  Google Scholar 

  7. 7.

    Bowling AC, Stewart TM (2004) Dietary supplements and multiple sclerosis: a health professional’s guide. Demos, New York

    Google Scholar 

  8. 8.

    Devinsky O, Schachter S, Pacia S (2005) Complementary and alternative therapies for epilepsy. Demos, New York

    Google Scholar 

  9. 9.

    Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, Van Rompay M, et al. (1998) Trends in alternative medicine use in the United States, 1990–1997: results of a follow-up national survey. JAMA 280:1569–1575

    PubMed  CAS  Article  Google Scholar 

  10. 10.

    Ernst E (1998) Harmless herbs? A review of the recent literature. Am J Med 104:170–178

    PubMed  CAS  Article  Google Scholar 

  11. 11.

    Ernst E, Casseleth BR (1998) The prevalence of complementary/alternative medicine in cancer: a systematic review. Cancer 83:777–782

    PubMed  CAS  Article  Google Scholar 

  12. 12.

    Gold SM, Mohr DC, Huitinga I, Flachenecker P, Sternberg EM, Heesen C (2005) The role of stress-response systems for the pathogenesis and progression of MS. Trends Immunol 26:644–652

    PubMed  CAS  Article  Google Scholar 

  13. 13.

    Henze T, Pette M, Rieckmann P, MS-Therapie Konsensus Gruppe (MSTKG) (2004) Symptomatic therapy of multiple sclerosis. Nervenarzt 75:2–39

    PubMed  Google Scholar 

  14. 14.

    Katz M (2005) Gemstone energy medicine. Natural Healing Press, Portland

    Google Scholar 

  15. 15.

    Kesselring J (2005) Symptomatic therapy and neurorehabilitation in multiple sclerosis. Lancet Neurol 4:643–652

    PubMed  Article  Google Scholar 

  16. 16.

    Kieseier BC, Hemmer B, Hartung HP (2005) Multiple sclerosis - novel insights and new therapeutic strategies. Curr Opin Neurol 18:211–220

    PubMed  CAS  Article  Google Scholar 

  17. 17.

    Lutz J (1998) Oxygen treatment methods - a critical analysis of established and controversial procedures (II). Versicherungsmedizin 50:190–194

    PubMed  CAS  Google Scholar 

  18. 18.

    McDonald WI, Compston DA, Edan G, Goodkin D, Hartung HP, Lublin FD, et al. (2001) Recommended diagnostic criteria for multiple sclerosis: guidelines from the international panel on the diagnosis of multiple sclerosis. Ann Neurol 50:121–127

    PubMed  CAS  Article  Google Scholar 

  19. 19.

    Mohr DC, Hart SL, Julian L, Cox D, Pelletier D (2004) Association between stressful life events and exacerbation in multiple sclerosis: a meta-analysis. BMJ 328:731–733

    PubMed  Article  Google Scholar 

  20. 20.

    Moschen R, Kemmler G, Schweigkofler H, Holzner B, Dunser M, Richter R, et al. (2001) Use of alternative/complementary therapy in breast cancer patients - a psychological perspective. Support Care Cancer 9:267–274

    PubMed  CAS  Article  Google Scholar 

  21. 21.

    Nayak S, Matheis RJ, Schoenberger NE, Shiflett SC (2003) Use of unconventional therapies by individuals with multiple sclerosis. Clin Rehabil 17:181–191

    PubMed  Article  Google Scholar 

  22. 22.

    Patti F, Ciancio MR, Reggio E, Lopes R, Palermo F, Cacopardo M, et al. (2002) The impact of outpatient rehabilitation on quality of life in multiple sclerosis. J Neurol 249:1027–1033

    PubMed  Article  Google Scholar 

  23. 23.

    Pearl PL, Robbins EL, Bennett HD, Conry JA (2005) Use of complementary and alternative therapies in epilepsy: cause for concern. Arch Neurol 62:1472–1475

    PubMed  Article  Google Scholar 

  24. 24.

    Pizzorno JE, Murray MT (2005) Textbook of natural medicine. Churchill Livingstone, Edinburgh

    Google Scholar 

  25. 25.

    Poser S, Paty DW, Scheinberg LC, McDonald WI, Davis FA, Ebers GC, et al. (1983) New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 13:227–231

    PubMed  CAS  Article  Google Scholar 

  26. 26.

    Rajendran PR, Thompson RE, Reich SG (2001) The use of alternative therapies by patients with Parkinson’s disease. Neurology 57:790–794

    PubMed  CAS  Google Scholar 

  27. 27.

    Rieckmann R, Toyka KV, MSTCG (2004) Escalating immunotherapy of multiple sclerosis. J Neurol 251:1329–1339

    PubMed  CAS  Article  Google Scholar 

  28. 28.

    Sadovnick AD, Ebers GC (1993) Epidemiology of multiple sclerosis: a critical overview. Can J Neurol Sci 20:17–29

    PubMed  CAS  Google Scholar 

  29. 29.

    Sastre-Garriga J, Munteis E, Rio J, Pericot I, Tintore M, Montalban X (2003) Unconventional therapy in multiple sclerosis. Mult Scler 9:320–322

    PubMed  Article  Google Scholar 

  30. 30.

    Schwartz CE, Laitin E, Brotman S, LaRocca N (1999) Utilization of unconventional treatments by persons with MS: is it alternative or complementary?. Neurology 52:626–629

    PubMed  CAS  Google Scholar 

  31. 31.

    Shealy CN (2000) The complete illustrustrated encyclopedia of alternative healing therapies. Könemann, Köln

    Google Scholar 

  32. 32.

    Sospedra M, Martin R (2005) Immunology of multiple sclerosis. Annu Rev Immunol 23:683–747

    PubMed  CAS  Article  Google Scholar 

  33. 33.

    Sparber A, Wootton JC (2002) Surveys of complementary and alternative medicine: Part V. Use of alternative and complementary therapies for psychiatric and neurologic diseases. J Altern Complement Med 8:93–96

    PubMed  Article  Google Scholar 

  34. 34.

    Steultjens EM, Dekker J, Bouter LM, Leemrijse CJ, van den Ende CH (2005) Evidence of the efficacy of occupational therapy in different conditions: an overview of systematic reviews. Clin Rehabil 19:247–254

    PubMed  Article  Google Scholar 

  35. 35.

    Wang Y, Hashimoto S, Ramsum D, Findlay B, Best A, Oger J (1999) A pilot study of the use of alternative medicine in multiple sclerosis patients with special focus an acupuncture. Neurology 52:A550

    Google Scholar 

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Author information

Affiliations

  1. Dept. of Neurology, University of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany

    Annett Apel, Brigitte Greim & Uwe K. Zettl

  2. Marianne Strauss Clinic, Berg/Kempfenhausen, Germany

    Nicolaus König

Authors
  1. Annett Apel
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  2. Brigitte Greim
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  3. Nicolaus König
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  4. Uwe K. Zettl
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Corresponding author

Correspondence to Annett Apel.

Additional information

Received in revised form: 28 February 2006

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Apel, A., Greim, B., König, N. et al. Frequency of current utilisation of complementary and alternative medicine by patients with multiple sclerosis. J Neurol 253, 1331–1336 (2006). https://doi.org/10.1007/s00415-006-0217-9

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Keywords

  • multiple sclerosis
  • complementary and alternative medicine (CAM)
  • illness-related factors
  • frequencies of CAM
  • subjective effectiveness of CAM