Journal of Neurology

, Volume 253, Issue 9, pp 1143–1146 | Cite as

Residual fatigue is independent of antecedent events and disease severity in Guillain-Barré syndrome

  • M.P.J. Garssen
  • R. Van Koningsveld
  • P.A. Van Doorn


The occurrence of severe fatigue after Guillain-Barré syndrome (GBS), and its relation with disease course, clinical characteristics, and antecedent infections was studied in 100 GBS patients. Severe fatigue, expressed as a mean Fatigue Severity Scale (FSS) score of 5.0 or more, was present in 60% of all patients. It was more frequently present in females and in patients over 50 years (p<0.01). There was no significant relationship between fatigue severity and the level of functional disability at nadir, antecedent events or infections, clinical variables, and time to follow-up after GBS.


Guillain-Barré syndrome fatigue disease severity antecedent events 


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Copyright information

© Steinkopff Verlag Darmstadt 2006

Authors and Affiliations

  • M.P.J. Garssen
    • 1
  • R. Van Koningsveld
    • 1
  • P.A. Van Doorn
    • 1
  1. 1.Departments of NeurologyErasmus University Medical Center RotterdamRotterdamThe Netherlands

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