Familial adolescent-onset scoliosis and later segmental dystonia in an Irish family
Adolescent-onset scoliosis occurs more frequently than expected in primary adult-onset cervical dystonia and a genetic association between the conditions has been postulated. The authors report a family in which four members have adult-onset cervical and/or brachial dystonia, two of whom have coexistent scoliosis. Four other individuals have isolated childhood- or adolescent-onset scoliosis. Adolescent-onset scoliosis may represent part of the dystonia phenotype in this family.
Key wordsprimary torsion dystonia scoliosis
Unable to display preview. Download preview PDF.
- 5.Domenech J, Tormos JM, Barrios C, et al. (1997) Abnormal cortico-cortical inhibition in idiopathic scoliosis. Is idiopathic scoliosis a dystonia? Neurology 48(suppl 2):A344 (Abstract)Google Scholar
- 7.Duane D (1998) Frequency of scoliosis in cervical dystonia patients and their relatives. Mov Disord 13(suppl 2):99.24 (Abstract)Google Scholar
- 13.Lowe TG, Edgar M, Margulies JY, Miller NH, Raso VJ, Reinker KA, Rivard C-H (2000) Aetiology of idiopathic scoliosis: current trends in research. J Bone Joint Surg (Am) 82:1157–1168Google Scholar
- 16.Reamy BV, Slakey JB (2001) Adolescent idiopathic scoliosis: review and current concepts. Am Fam Phys 64:32–35Google Scholar