Advertisement

International Journal of Legal Medicine

, Volume 114, Issue 4–5, pp 229–231 | Cite as

MtDNA control region and RFLP data for Sicily and France

  • F. Cali
  • M. G. Le Roux
  • R. D’Anna
  • A. Flugy
  • G. De Leo
  • V. Chiavetta
  • G. F. Ayala
  • V. Romano
Original article

Abstract

The forensic application of mtDNA typing requires large databases which are regionally well defined. To further this aim, we have typed mtDNA in a sample of 111 French and 106 Sicilians. The French were typed for both hypervariable segments (HVR1 and HVR2) of the mtDNA control region, whereas the Sicilians were only typed for HVR1, but in addition for the coding region RFLP markers for mtDNA groups H, I, J, K, L, M, T, U, V and X. In both samples, the predominant sequence type by far was the Cambridge reference sequence. Comparing HVR1 sequences, we found that the French sample was twice as diverse as the Sicilian sample as measured by sequence matches. A further set of sequence match comparisons including the French, Sicilian, and the published British mtDNA samples, demonstrate that sequence matching probabilities within samples differ by less than a factor of 2 from the matching probabilities between samples.

Keywords MtDNA RFLP typing Population study 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Supplementary material

414_2001_Article_229_MOESM1_ESM.pdf (10 kb)
Table S1 MtDNA HVR1 and HVR2 sequences for 111 unrelated French individuals (PDF 10 KB)
414_2001_Article_229_MOESM2_ESM.pdf (14 kb)
Table S2 MtDNA HVR1 sequences and RFLP typing for 106 Sicilians from Castellammare del Golfo (PDF 13 KB)

Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • F. Cali
    • 1
  • M. G. Le Roux
    • 2
  • R. D’Anna
    • 3
  • A. Flugy
    • 3
  • G. De Leo
    • 3
  • V. Chiavetta
    • 1
  • G. F. Ayala
    • 1
  • V. Romano
    • 1
  1. 1.OASI Istituto per la Ricerca sul Ritardo Mentale e l’Involuzione Cerebrale (IRCCS)Troina (Enna)Italy
  2. 2.Institut de BiologieCentre Hospitalier Universitaire de NantesNantesFrance
  3. 3.Dipartimento di Biopatologia e Metodologie Biomediche, Facoltà di Medicina e ChirurgiaUniversitàdegli Studi di PalermoPalermoItaly

Personalised recommendations