Paternal lineages and forensic parameters based on 23 Y-STRs (Powerplex® Y23) in Mestizo males from Mexico City
We analyzed 307 Mexican-Mestizo (admixed) males from Mexico City with the Powerplex® Y23 system. The complete list of Y-STR haplotypes was uploaded into the YHRD database (accession number YA004275). The discriminatory capacity (98.70 %) and gene diversity (D = 99.99 %) were calculated, improving the haplotype diversity regarding previous studies in Mexico based on 17 Y-STRs and 12 Y-STRs. Haplogroup distribution assignment was inferred by means of two different online-available algorithms. The Native American Q* haplogroup was the most frequent (66.2 %), followed by the European R1b lineage (19.5 %). In addition, eight Eurasian (3.9%) and two African (6.6%) haplogroups were observed in this population sample from Mexico City. Interestingly, AMOVA test showed a low but significant differentiation among Mexican-Mestizos (Fst = 1.52%; p = 0.0000), suggesting that four population clusters allow to explain their genetic structure according to geographic criteria: north, west, center, and south.
KeywordsY-STRs Mexico City Mestizos Powerplex® Y23 Haplogroup inference
The authors thank all volunteers included in this study.
Compliance with ethical standards
For this purpose, we recruited 307 volunteers from Mexico City who signed a consent form before to the inclusion in our study, according to the ethical guidelines of the Helsinki Declaration. The anonymity of these individuals was preserved at all times. This project was approved by the Ethical Research Committee at the Instituto de Ciencias Forenses (INCIFO) of Mexico City.
Conflict of interest
The authors declare that they have no conflict of interest.
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