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Population data of 23 Y chromosome STR loci for the five major human subpopulations of Ghana

  • Abban Edward Kofi
  • Hashom Mohd Hakim
  • Hussein Omar Khan
  • Siti Afifah Ismail
  • Anita Ghansah
  • Agyemang Adjem David
  • Nor Fazila Che Mat
  • Geoffrey Keith Chambers
  • Hisham Atan EdinurEmail author
Population Data

Abstract

In this study, 268 samples for unrelated males belonging to the five major human subpopulation groups in Ghana (Akan, Ewe, Mole-Dagbon, Ga-Dangme and Guang) were genetically characterised for 23 Y chromosome short tandem repeat (STR) loci using the Powerplex® Y23 STR kit. A total of 263 complete haplotypes were recorded of which 258 were unique. The haplotype diversity, discriminating capacity and match probability for the pooled population data were 0.9998, 0.9627 and 0.0039, respectively. The pairwise genetic distance (RST) for the Ghanaian datasets and other reference populations deposited in the Y-STR Haplotype Reference Database (YHRD) were estimated and mapped using multidimensional scaling (MDS) plot. The Guang and Ewe were significantly different from the Akan, Mole-Dagbon and Ga-Dangme. However, the five Ghanaian datasets were all plotted close together with other African populations in the MDS data mapping.

Keywords

Ghana Y chromosome STR Haplotypes Population genetics Forensic science 

Notes

Acknowledgements

We thank all the donors for providing samples for this study and all organisations and individuals that assisted in sample recruitment. We also thank the Inspector General of Police of Ghana and Inspector General of Police Malaysia for supporting this study. We thank Prof Lutz Roewer for providing blind samples for quality control. We are grateful to Royal Malaysia Police for technical supports and laboratory facility. Geoff Chambers thanks VUW for alumnus support.

Funding information

This study received financial support from Ghana Education Trust Fund (no. 304/PPSK/6150145/G112) and Bridging Grant, Universiti Sains Malaysia (no. 304/PPSK/6316132).

Compliance with ethical standards

This study was approved by the Institutional Review Board of Noguchi Memorial Institute of Medical Research, University of Ghana, and Human Ethics Committee, Universiti Sains Malaysia.

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

414_2019_2099_MOESM1_ESM.docx (15 kb)
ESM 1 (DOCX 14 kb)
414_2019_2099_MOESM2_ESM.docx (56 kb)
ESM 2 (DOCX 55 kb)
414_2019_2099_MOESM3_ESM.xlsx (110 kb)
ESM 3 (XLSX 109 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Abban Edward Kofi
    • 1
    • 2
  • Hashom Mohd Hakim
    • 3
    • 4
  • Hussein Omar Khan
    • 3
  • Siti Afifah Ismail
    • 3
  • Anita Ghansah
    • 5
  • Agyemang Adjem David
    • 2
  • Nor Fazila Che Mat
    • 1
  • Geoffrey Keith Chambers
    • 6
  • Hisham Atan Edinur
    • 1
    • 7
    • 8
    Email author
  1. 1.School of Health SciencesUniversiti Sains MalaysiaKubang KerianMalaysia
  2. 2.Forensic Science Laboratory, Criminal Investigation DepartmentGhana Police ServiceAccraGhana
  3. 3.DNA Databank Division (D13), Criminal Investigation DepartmentRoyal Malaysian PoliceCherasMalaysia
  4. 4.School of Industrial TechnologiesUniversiti Sains MalaysiaGelugorMalaysia
  5. 5.Noguchi Memorial Institute for Medical ResearchUniversity of GhanaAccraGhana
  6. 6.School of Biological SciencesVictoria University of WellingtonWellingtonNew Zealand
  7. 7.Institute of Tropical Biodiversity and Sustainable DevelopmentUniversiti Malaysia TerengganuKuala NerusMalaysia
  8. 8.Environmental Futures Research InstituteGriffith UniversityNathanAustralia

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