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Phylogenetic analysis and haplotype diversity in Christian residents of Lahore, Pakistan, using 17 Y-chromosomal STR loci

  • Samia Saleem
  • Ahmad Ali Shahid
  • Muhammad ShafiqueEmail author
  • Aqsa Rubab
  • Faqeeha Javed
  • Tayyab Husnain
Population Data
  • 27 Downloads

Abstract

This population data pertains to 250 unrelated male residents of the Christian population of Lahore, Pakistan. AmpF/STR®Yfiler PCR amplification kit was utilized for evaluation of 17 Y-chromosomal STRs loci. Ancestral lineages and parameters of forensic importance were examined leading to recognition of 135 unique out of 175 total haplotypes with diversity value of 0.991. All Y-STRs portrayed high discrimination power where DYS385 depicted the maximum value of 0.917. Multidimensional Scaling (MDS) and Analysis of Molecular Variance (AMOVA) were generated using YHRD (Y-Chromosome STR Haplotype Reference Database) tools. A pair-wise genetic distance comparison using Rst, Fst, and associated p values lead to the conclusion that studied Christian community was significantly demarcated from the rest of the global populations.

Keywords

Haplotype diversity Y-chromosomal STRs Polymorphism Christian population 

Notes

Acknowledgments

The authors acknowledge the volunteers and management of St. Francis Catholic Church and St. Paul’s Anglican Church, Lahore, for their cooperation and moral support.

Supplementary material

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Samia Saleem
    • 1
  • Ahmad Ali Shahid
    • 1
  • Muhammad Shafique
    • 1
    Email author
  • Aqsa Rubab
    • 1
  • Faqeeha Javed
    • 1
  • Tayyab Husnain
    • 1
  1. 1.Forensic DNA Typing Research Laboratory, Centre of Excellence in Molecular BiologyUniversity of the PunjabLahorePakistan

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